Complement Factor B Antikörper (Fragment Bb)

Produktnummer ABIN181113

Der Maus Monoklonal anti-Complement Factor B Antikörper (Klon 10-09-14) (ABIN181113) detektiert spezifisch Complement Factor B in WB, FACS, EIA und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Complement Factor B Antikörper (Fragment Bb) (ABIN181113)

Target: Complement Factor B (CFB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 10-09-14

Produktdetails anti-Complement Factor B Antikörper

Bindungsspezifität: Fragment Bb

Spezifität: This antibody recognises the Bb fragment of 90 kDa complement factor B, present in blood serum.

Produktmerkmale: Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Human factor B

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: This antibody binds to both the Bb fragment and complement factor B so is notsuitable for all ELISA applications. Western Blot. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptocial glomerlulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Borate buffered saline containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Complement Factor B

Target: Complement Factor B (CFB)

Andere Bezeichnung: Complement Factor B

Hintergrund: C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Gen-ID: 629

UniProt: P00751

Pathways: Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process