CD40 Antikörper

Produktnummer ABIN1804378

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD40 in FACS, IHC, IP, ICC, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD40 Antikörper (ABIN1804378)

Target: CD40

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CD40 Antikörper

Spezifität: Recognizes human CD40 cell surface antigen, a 48kD glycoprotein expressed by B lymphocytes and weakly by some monocytes. CD40 is involved in the process of B cell selection in germinal centers and is vital in T cell-B cell interactions.

Aufreinigung: Protein A purified

Immunogen:

Type of Immunogen: Native protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: Flo (20 μg/mL), ICC (1:10), IHC, IHC-Fr, IHC-P (10 μg/mL), IP

Usage: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Flow Cytometry: 20 μg/mL. Use 10 μL to lane 1 x10⁶ in 100 μL. Immunohistochemistry (Frozen and paraffin): 1-10 μg/mL. Requires protein digestion pre-treatment of paraffin embedded sections prior to staining. Immunocytochemistry: 1:10 μg/mL. Positive control: Human tonsil.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: TBS,  pH 7.4, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid freeze-thaw cycles.

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund: Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

Gen-ID: 958

UniProt: P25942

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints