MEK2 Antikörper

Produktnummer ABIN1724726

Produktdetails anti-MEK2 Antikörper

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MEK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human MAP2K2 expressed in E. coli.

Klon: 7F5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu MEK2

Target: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Andere Bezeichnung: MAP2K2 (MAP2K2 Produkte)

Synonyme: CFC4 antikoerper, MAPKK2 antikoerper, MEK2 antikoerper, MKK2 antikoerper, PRKMK2 antikoerper, AA589381 antikoerper, MK2 antikoerper, Prkmk2 antikoerper, ATMKK2 antikoerper, F27B13.50 antikoerper, F27B13_50 antikoerper, MAP KINASE KINASE 1 antikoerper, MAP kinase kinase 2 antikoerper, MK1 antikoerper, map2k2 antikoerper, wu:fa56c06 antikoerper, zgc:123171 antikoerper, zgc:172250 antikoerper, mitogen-activated protein kinase kinase 2 antikoerper, mitogen activated protein kinase kinase 2 antikoerper, MAP kinase kinase 2 antikoerper, mitogen-activated protein kinase kinase 2a antikoerper, mitogen-activated protein kinase kinase 2b antikoerper, MAP2K2 antikoerper, Map2k2 antikoerper, MKK2 antikoerper, map2k2a antikoerper, map2k2b antikoerper

Hintergrund:

Description: MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax.

Aliases: MEK2, MKK2, MAPKK2

Molekulargewicht: 44 kDa

Gen-ID: 5605

HGNC: 5605

Pathways: MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling