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MAPK10 Antikörper (AA 28-233)

MAPK10 Reaktivität: Human, Maus WB, ELISA, ICC Wirt: Maus Monoclonal 10E4A4 unconjugated
Produktnummer ABIN1724701
  • Target Alle MAPK10 Antikörper anzeigen
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    Bindungsspezifität
    • 15
    • 11
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-233
    Reaktivität
    • 64
    • 50
    • 36
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 67
    • 8
    • 3
    Maus
    Klonalität
    • 60
    • 20
    Monoklonal
    Konjugat
    • 35
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAPK10 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 38
    • 26
    • 13
    • 13
    • 9
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    Verwendungszweck
    MAPK10 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli.
    Klon
    10E4A4
    Isotyp
    IgG1
    Top Product
    Discover our top product MAPK10 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tamma, Kalyanaraman, Pahwa, Dominguez, Modesto: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).

    Kinet, Bernard, Mongellaz, Perreau, Goldman, Taylor: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).

  • Target
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    Andere Bezeichnung
    MAPK10 (MAPK10 Produkte)
    Hintergrund
    MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Molekulargewicht
    53 kDa
    NCBI Accession
    NP_002744
    UniProt
    P53779
    Pathways
    MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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