RAD50 Antikörper (C-Term)
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- Target Alle RAD50 Antikörper anzeigen
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
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Bindungsspezifität
- AA 911-938, C-Term
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAD50 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Mouse Rad50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-938 amino acids from the C-terminal region of mouse Rad50.
- Klon
- RB40014
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RAD50 Primärantikörper
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anti-RAD50 Homolog (S. Cerevisiae) (RAD50) antibody
RAD50 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 228-359) antibodyRAD50 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 3D2G10 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 1-100) antibodyRAD50 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 672-786) antibodyRAD50 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 13-RAD50 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 228-359) antibodyRAD50 Reaktivität: Human ELISA Wirt: Maus Monoclonal 5A8E5 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (Internal Region) antibodyRAD50 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 1-234) antibodyRAD50 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) antibodyRAD50 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 817-872) antibodyRAD50 Reaktivität: Human, Maus WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 700-750) antibodyRAD50 Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Hund IHC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Mouse Rad50 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
- Andere Bezeichnung
- Rad50 (RAD50 Produkte)
- Hintergrund
- Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point. The complex may also be required for DNA damage signaling via activation of the ATM kinase. In telomeres the MRN complex may modulate t-loop formation (By similarity).
- Molekulargewicht
- 153488
- Gen-ID
- 19360
- UniProt
- P70388
- Pathways
- DNA Reparatur, Protein targeting to Nucleus
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