Caspase 8 Antikörper (Cleaved-Asp384)
Kurzübersicht für Caspase 8 Antikörper (Cleaved-Asp384) (ABIN1536108)
Target
Alle Caspase 8 (CASP8) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 335-384, Cleaved-Asp384
-
Spezifität
-
Caspase 8 (Cleaved-Asp384) Antibody detects endogenous levels of fragment of activated Caspase 8 resulting from cleavage adjacent to Asp384.
-
Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
-
Reinheit
- > 95 %
-
Immunogen
- The antiserum was produced against synthesized peptide derived from human Caspase 8.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500~1:1000 ELISA: 1:40000
-
Kommentare
-
Unigene-Number: Hs.599762 (NCBI Gene Symbol: CASP8)
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
-
Haltbarkeit
- 12 months
-
-
-
: "Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 28, Issue 3, pp. 419-25, (2014) (PubMed).
-
: "Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 28, Issue 3, pp. 419-25, (2014) (PubMed).
-
- Caspase 8 (CASP8)
-
Andere Bezeichnung
- Caspase 8
-
Hintergrund
-
Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
NCBI Gene Symbol: CASP8
-
Molekulargewicht
- 47 and 55 kDa
-
Gen-ID
- 841
-
OMIM
- 211980
-
UniProt
- Q14790
-
Pathways
- Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Target
-