IFI16 Antikörper (AA 731-780)

Produktnummer ABIN1534925

Der Kaninchen Polyklonal anti-IFI16 Antikörper (ABIN1534925) detektiert spezifisch IFI16 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für IFI16 Antikörper (AA 731-780) (ABIN1534925)

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFI16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IFI16 Antikörper

Bindungsspezifität: AA 731-780

Verwendungszweck: IFI-16 Antibody

Spezifität: IFI-16 Polyclonal Antibody detects endogenous levels of IFI-16 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IFI16. AA range:731-780

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu IFI16

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Andere Bezeichnung: IFI16

Hintergrund:

Synonyms: IFI16, IFNGIP1, Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator

Background: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011],

Gene Name: IFI16

Protein Name: Gamma-interferon-inducible protein 16

Molekulargewicht: 88 kDa

Gen-ID: 3428

OMIM: 147586

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagie, Inflammasome