Caspase 8 Antikörper (pTyr380)
Kurzübersicht für Caspase 8 Antikörper (pTyr380) (ABIN1532005)
Target
Alle Caspase 8 (CASP8) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 346-395, pTyr380
-
Spezifität
-
Caspase 8 (Phospho-Tyr380) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Tyr380.
PhosphorylationH:Y380
-
Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
-
Reinheit
- > 95 %
-
Immunogen
- The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Tyr380.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500~1:1000 ELISA: 1:10000
-
Kommentare
-
Unigene-Number: Hs.599762 (NCBI Gene Symbol: CASP8)
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
-
Haltbarkeit
- 12 months
-
-
-
: "Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33263-71, (2013) (PubMed).
-
: "Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33263-71, (2013) (PubMed).
-
- Caspase 8 (CASP8)
-
Andere Bezeichnung
- Caspase 8
-
Hintergrund
-
Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
NCBI Gene Symbol: CASP8
-
Molekulargewicht
- 55 kDa
-
Gen-ID
- 841
-
OMIM
- 211980
-
UniProt
- Q14790
-
Pathways
- Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Target
-