JAK2 Antikörper (pTyr221)
Kurzübersicht für JAK2 Antikörper (pTyr221) (ABIN1531883)
Target
Alle JAK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 191-240, pTyr221
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Spezifität
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JAK2 (Phospho-Tyr221) Antibody detects endogenous levels of JAK2 only when phosphorylated at Tyr221.
PhosphorylationH:Y221 M:Y221 R:Y221
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human JAK2 around the phosphorylation site of Tyr221.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
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Kommentare
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Unigene-Number: Hs.656213 (NCBI Gene Symbol: JAK2)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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- JAK2 (Janus Kinase 2 (JAK2))
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Andere Bezeichnung
- JAK2
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Hintergrund
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Synonyms: JAK-2, JAK2, Janus kinase 2, kinase Jak2
NCBI Gene Symbol: JAK2
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Molekulargewicht
- 130 kDa
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Gen-ID
- 3717
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OMIM
- 147796
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UniProt
- O60674
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Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
Target
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