GATA4 Antikörper (pSer105)
Kurzübersicht für GATA4 Antikörper (pSer105) (ABIN1531603)
Target
Alle GATA4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 71-120, pSer105
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Verwendungszweck
- GATA-4 (phospho Ser105) Antibody
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Spezifität
- Phospho-GATA-4 (S105) Polyclonal Antibody detects endogenous levels of GATA-4 protein only when phosphorylated at S105.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human GATA4 around the phosphorylation site of Ser105. AA range:71-120
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- GATA4 (GATA Binding Protein 4 (GATA4))
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Andere Bezeichnung
- GATA4
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Hintergrund
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Synonyms: GATA4, Transcription factor GATA-4, GATA-binding factor 4
Background: This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Gene Name: GATA4
Protein Name: Transcription factor GATA-4
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Molekulargewicht
- 44 kDa
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Gen-ID
- 2626
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OMIM
- 600576
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UniProt
- P43694
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Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
Target
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