CD46 Antikörper
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD46 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Aufreinigung
- Protein A agarose
- Immunogen
- Human pancreatic carcinoma cell line (AsPC1)
- Klon
- TGP3
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD46 Primärantikörper
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anti-CD46 (CD46) (AA 35-179) antibody
CD46 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 Reaktivität: Human WB, FACS, ELISA, ICC Wirt: Maus Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) (AA 40-320) antibodyCD46 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 Reaktivität: Human WB, FACS, IF, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 Reaktivität: Human, Maus WB, FACS, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibody (Biotin)CD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibody (FITC)CD46 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal MEM-258 FITC
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Upon receipt, store (in aliqouts) at -20 °C.
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- Target
- CD46
- Andere Bezeichnung
- CD46 / MCP (CD46 Produkte)
- Hintergrund
- CD46, also known as membrane cofactor protein (MCP), was first described as a membrane complement regulator that fu nctions as a cofactor with factor I to cleave complement factors C3b and C4b and thereby protect the cell from co mplement attack. In humans, CD46 is expressed on all nuc leated cells. In the rodent animals, its expression is limited only in testis, indicating that the major function of CD46 among different species lies in fertilization. CD46 and other membrane complement regulatory proteins (CD55 and CD59) are frequently overexpressed on cancer cells, possibly as a mechanism for cancer cells to overcome lysis by complement. Several pathogens, including viruses and bacteria (measles virus, human herpesvirus 6, human group B and D adenoviruses, Streptococcus pyogenes , and pathogenic Neisseria species) have been reported to use CD46 for invasion. Recent evidence also indicates that CD 46 signaling events play an important role in linking innate and acquired immune function.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
- Gen-ID
- 9606
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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