TLR4 Antikörper (PE)
-
- Target Alle TLR4 Antikörper anzeigen
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
Reaktivität
- Maus
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser TLR4 Antikörper ist konjugiert mit PE
-
Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody reacts with mouse TLR4/MD-2 complex.
- Aufreinigung
- Protein A agarose
- Immunogen
- Mouse TLR4/MD-2 transfected Ba/F3 cell
- Klon
- UT15
- Isotyp
- IgG1
- Top Product
- Discover our top product TLR4 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- 50 tests in 1 mLPBS containing 1 % BSA and 0.09 % NaN3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8 °C.
-
- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Andere Bezeichnung
- CD284 / TLR4 (TLR4 Produkte)
- Hintergrund
- Toll, a Drosophila receptor molecule with extracellular leucine-rich repeat (LRR), has a role in triggering innate defenses against bacteria or fungi. TLR4 (Toll-like receptor 4) is a member of TLR family, which is human homologue of Toll protei n. It has extracellular LRR and an intracellular signaling domain, which is similar to the type I IL-1 receptor. TLR4 is expressed in subpopulations of cells including myeloid cells, B cells, monocytes, and endothelial cells. Recent studies have suggested that TLR4 might act as a receptor for LPS (lipopolysaccharide). TLR4 alone is not capable of sensing and signaling the presence of LPS, but another molecule MD-2, which is physically associated with TLR4, is required for LPS recognition through TLR4.Synonyms: Toll-like receptor 4
- Gen-ID
- 21898
- NCBI Accession
- NP_067272
- UniProt
- Q9QUK6
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
-