IL-6 Antikörper

Produktnummer ABIN1383946

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IL-6 in WB, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für IL-6 Antikörper (ABIN1383946)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: B-F6

Produktdetails anti-IL-6 Antikörper

Spezifität: Recognises both natural and recombinant human IL-6

Aufreinigung: Ion exchange chromatography

Sterilität: 0.22 μm filtered

Immunogen: Recombinant human IL-6,Myeloma X63/AG.8653 x Balb/c spleen cells

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Referenzen für anti-IL-6 Antikörper (ABIN1383946)

Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: "STAT3 is constitutively activated in Hodgkin cell lines." in: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).

Voorzanger, Touitou, Garcia, Delecluse, Rousset, Joab, Favrot, Blay: "Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors." in: Cancer research, Vol. 56, Issue 23, pp. 5499-505, (1997) (PubMed).

Wijdenes, Heinrich, Müller-Newen, Roche, Gu, Clément, Klein: "Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies." in: European journal of immunology, Vol. 25, Issue 12, pp. 3474-81, (1996) (PubMed).

Zunino, Singh, Bass, Picker: "Immunodetection of histone epitopes correlates with early stages of apoptosis in activated human peripheral T lymphocytes." in: The American journal of pathology, Vol. 149, Issue 2, pp. 653-63, (1996) (PubMed).

Wijdenes, Clement, Klein, Morel-Fourrier, Vita, Ferrara, Peters: "Human recombinant dimeric IL-6 binds to its receptor as detected by anti-IL-6 monoclonal antibodies." in: Molecular immunology, Vol. 28, Issue 11, pp. 1183-92, (1992) (PubMed).

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL-6

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome