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c-MET Antikörper

MET Reaktivität: Human FACS, cELISA Wirt: Ratte Monoclonal BCI-3E7 unconjugated
Produktnummer ABIN1381745
  • Target Alle c-MET (MET) Antikörper anzeigen
    c-MET (MET) (Met Proto-Oncogene (MET))
    Reaktivität
    • 250
    • 144
    • 98
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 222
    • 39
    • 3
    • 1
    Ratte
    Klonalität
    • 210
    • 55
    Monoklonal
    Konjugat
    • 131
    • 20
    • 13
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser c-MET Antikörper ist unkonjugiert
    Applikation
    • 182
    • 105
    • 50
    • 43
    • 31
    • 27
    • 26
    • 24
    • 15
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Spezifität
    Anti-human c-Met
    Produktmerkmale
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Aufreinigung
    Protein G
    Immunogen
    genetic immunisation with cDNA encoding human c-Met
    Klon
    BCI-3E7
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product MET Primärantikörper
  • Applikationshinweise
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C
    Informationen zur Lagerung
    short term: 2 °C - 8 °C, long term: -20 °C
  • Target
    c-MET (MET) (Met Proto-Oncogene (MET))
    Andere Bezeichnung
    c-Met (MET Produkte)
    Synonyme
    AUTS9 antikoerper, HGFR antikoerper, RCCP2 antikoerper, c-Met antikoerper, AI838057 antikoerper, HGF antikoerper, Par4 antikoerper, Hgfr antikoerper, c-met antikoerper, MET antikoerper, C-MET antikoerper, met antikoerper, met-A antikoerper, MET proto-oncogene, receptor tyrosine kinase antikoerper, met proto-oncogene antikoerper, MET proto-oncogene, receptor tyrosine kinase L homeolog antikoerper, MET antikoerper, Met antikoerper, met.L antikoerper
    Hintergrund
    C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Single-pass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
    UniProt
    P08581
    Pathways
    RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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