CTLA4 Antikörper

Produktnummer ABIN135317

Der Hamster Monoklonal anti-CTLA4 Antikörper wird verwendet zum Nachweis von CTLA4 in Proben von Maus. Er wurde validiert für FACS, ELISA und St.

Kurzübersicht für CTLA4 Antikörper (ABIN135317)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Stimulation (St)

Klon: 1B8

Produktdetails anti-CTLA4 Antikörper

Verwendungszweck: Hamster Anti-Mouse CD152-LE/AF

Spezifität: Mouse CD152, Mr 33-37 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD152 antibody for use in flow cytometry, ELISA, and stimulation assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: Extracellular portion of murine CTLA-4 fused to a murine IgG2a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CD152

Hintergrund: The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer, and is relatively conserved among humans, mice and chickens.

Gen-ID: 12477

UniProt: P09793

Pathways: Cancer Immune Checkpoints