Cyclin A Antikörper

Produktnummer ABIN121516

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin A in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Cyclin A Antikörper (ABIN121516)

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Cyclin A Antikörper

Spezifität: This product was prepared from monospecific antiserum by delipidation and defibrination. Antiserum will specifically react with a 60 kDa Cyclin A protein from Human, Rat and Mouse tissue. No reaction was observed against other related Cyclins. Cross reactivity with Cyclin A from other species may also occur.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Rat and Mouse.

Aufreinigung: Delipidation and defibrination.

Immunogen: Full length GST fusion protein corresponding to the human cyclin A gene

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. ELISA: 1/500-1/2000. Western blot: 1/250-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 80 mg/mL (by Refractometry)

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu Cyclin A

Target: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Andere Bezeichnung: Cyclin A2

Hintergrund: Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2 phase.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2

UniProt: P20248

Pathways: PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA