CD11b Antikörper (FITC)
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- Target Alle CD11b (ITGAM) Antikörper anzeigen
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD11b Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The antibody MEM-174 recognizes CD11b antigen (Mac-1), a 165 kDa transmembrane protein type 1 mainly expressed on monocytes, granulocytes and NK-cells. The CD11b mediates neutrophil and monocyte interactions with stimulated endothelium.
- Immunogen
- Human granulocytes
- Klon
- MEM-174
- Isotyp
- IgG2a
- Top Product
- Discover our top product ITGAM Primärantikörper
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anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM Reaktivität: Human, Maus, Ratte FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 145-340) antibodyITGAM Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM Reaktivität: Human, Maus, Ratte FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM Reaktivität: Ratte IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-174 PE
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM Reaktivität: Human IHC, WB, StM Wirt: Maus Monoclonal ITGAM-3338 unconjugated
anti-Integrin alpha M (ITGAM) (AA 623-728) antibodyITGAM Reaktivität: Human ELISA, ICC Wirt: Maus Monoclonal 3A10H5 unconjugated
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- Applikationshinweise
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Flow Cytometry (use 20 μL to label 10^6 cells or 100 μL whole blood).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
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Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Andere Bezeichnung
- CD11b (ITGAM Produkte)
- Hintergrund
- CD11b (integrin aM subunit) is a 165 kDa type I transmembrane glycoprotein that non-covalently associates with integrin b2 subunit (CD18), expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
- Gen-ID
- 3684
- UniProt
- P11215
- Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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