TNF alpha Antikörper
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- Target Alle TNF alpha Antikörper anzeigen
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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Reaktivität
- Maus, Ratte
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNF alpha Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Aufreinigung
- Affinity Chromatography on Protein G
- Endotoxin-Niveau
- less than 0.01 EU/μg
- Immunogen
- Recombinant Murine TNF alpha expressed in E. coli.
- Klon
- MP6-XT22
- Isotyp
- IgG1
- Top Product
- Discover our top product TNF alpha Primärantikörper
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- Applikationshinweise
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Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, Membrane permeabilisation is required for this application. ELISA: 1 μg/mL - 10 μg/mL. Functional Assays. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4 without preservatives., None, None
- Konservierungsmittel
- Without preservative
- Handhabung
- This product is photosensitive and should be protected from light
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody at 2 - 8 °C. DO NOT FREEZE!
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- Target
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
- Andere Bezeichnung
- Tumor Necrosis Factor (TNF-Alpha) (TNF alpha Produkte)
- Hintergrund
- TNF alpha is a 17 KDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a 26KDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumour cell lines, and has an important immuno-regulatory role.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
- Gen-ID
- 10090
- UniProt
- P06804
- Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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