CD14 Antikörper

Produktnummer ABIN118509

Der Maus Monoklonal anti-CD14 Antikörper (Klon Tük4) (ABIN118509) detektiert spezifisch CD14 in FACS, WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Affe, Schwein, Hund, Rind (Kuh), Schaf, Kaninchen, Ziege, Cat und Nerz.

Kurzübersicht für CD14 Antikörper (ABIN118509)

Target: CD14

Reaktivität: Human, Affe, Schwein, Hund, Rind (Kuh), Schaf, Kaninchen, Ziege, Cat, Nerz

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD14 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: Tük4

Produktdetails anti-CD14 Antikörper

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Goat, Cat, Rabbit, Mink, Bovine, Porcine,Sheep, Cynomolgus Monkey, Llama.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein G.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/50 - 1/200, use 5 μL of suggested working dilution to label 10^6 cells or 100 μL whole blood. ELISA. Western Blot under reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund: CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidyl-inositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

Gen-ID: 9606

UniProt: P08571

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades