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CD11b Antikörper

Der Ratte Monoklonal Anti-CD11b-Antikörper wurde für FACS, IP, IHC (fro) und IHC (p) validiert. Er ist geeignet, CD11b in Proben von Human, Maus und Kaninchen zu detektieren.
Produktnummer ABIN118145

Kurzübersicht für CD11b Antikörper (ABIN118145)

Target

Alle CD11b (ITGAM) Antikörper anzeigen
CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität

  • 338
  • 192
  • 78
  • 33
  • 21
  • 20
  • 17
  • 15
  • 11
  • 10
  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
Human, Maus, Kaninchen

Wirt

  • 211
  • 123
  • 119
  • 2
  • 1
  • 1
Ratte

Klonalität

  • 348
  • 105
  • 2
Monoklonal

Konjugat

  • 151
  • 41
  • 37
  • 29
  • 20
  • 10
  • 8
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD11b Antikörper ist unkonjugiert

Applikation

  • 302
  • 145
  • 120
  • 103
  • 66
  • 49
  • 41
  • 40
  • 39
  • 24
  • 20
  • 14
  • 14
  • 13
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

M1-70
  • Aufreinigung

    Ion Exchange Chromatography

    Immunogen

    T cell enriched splenocytes from B10 mice. Spleen cells from immunised DA rats were fused with cells of the NS1/1.Ag4.1 mouse myeloma cell line.

    Isotyp

    IgG2b
  • Applikationshinweise

    Immunoprecipitation. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections. Flow cytometry: 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Clone M1/70.15 has been reported to block iC3b binding to its receptor. ABIN118139 is recommended for this purpose.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS, 0.09 % Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    Andere Bezeichnung

    CD11b

    Hintergrund

    CD11b is a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor

    Gen-ID

    10090

    UniProt

    P05555

    Pathways

    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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