CD14 Antikörper

Produktnummer ABIN1177335

Zitiert in 1 Publikation. Der Maus Monoklonal anti-CD14 Antikörper (Klon M5E2) (ABIN1177335) detektiert spezifisch CD14 in FACS und Neut. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Cynomolgus, Rhesusaffen, Pavian und Hund.

Kurzübersicht für CD14 Antikörper (ABIN1177335)

Target: CD14

Reaktivität: Human, Cynomolgus, Rhesusaffen, Pavian, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD14 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Neutralization (Neut)

Klon: M5E2

Produktdetails anti-CD14 Antikörper

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotyp: IgG2a kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Referenzen für anti-CD14 Antikörper (ABIN1177335)

Wright, Ramos, Tobias, Ulevitch, Mathison: "CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein." in: Science (New York, N.Y.), Vol. 249, Issue 4975, pp. 1431-3, (1990) (PubMed).

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund: The M5E2 monoclonal antibody specifically binds to CD14, a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
Synonyms: LPS receptor, LPS-R, Myeloid cell-specific leucine-rich glycoprotein

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades