CD14 Antikörper
Kurzübersicht für CD14 Antikörper (ABIN1177335)
Target
Alle CD14 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Marke
- BD Pharmingen™
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Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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Isotyp
- IgG2a kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein." in: Science (New York, N.Y.), Vol. 249, Issue 4975, pp. 1431-3, (1990) (PubMed).
: "
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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein." in: Science (New York, N.Y.), Vol. 249, Issue 4975, pp. 1431-3, (1990) (PubMed).
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- CD14
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Andere Bezeichnung
- CD14
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Hintergrund
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The M5E2 monoclonal antibody specifically binds to CD14, a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
Synonyms: LPS receptor, LPS-R, Myeloid cell-specific leucine-rich glycoprotein -
Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
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