CD11b Antikörper
Kurzübersicht für CD11b Antikörper (ABIN1176910)
Target
Alle CD11b (ITGAM) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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Immunogen
- Human monocytes
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Isotyp
- IgG1 kappa
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anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 520-570) antibodyITGAM Reaktivität: Human, Maus, Ratte FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM Reaktivität: Human, Maus, Ratte FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM Reaktivität: Ratte IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-174 PE
anti-Integrin alpha M (ITGAM) (AA 623-728) antibodyITGAM Reaktivität: Human ICC, ELISA Wirt: Maus Monoclonal 3A10H5 unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM Reaktivität: Human IHC, WB, StM Wirt: Maus Monoclonal ITGAM-3340 unconjugated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Andere Bezeichnung
- CD11b/Mac-1
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Hintergrund
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The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin beta2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
Synonyms: Mac-1alpha, integrin alphaM subunit, CR3 alpha chain -
Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Target
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