AMACR Antikörper

Produktnummer ABIN115448

Der Kaninchen Polyklonal anti-AMACR Antikörper wird verwendet zum Nachweis von AMACR in Proben von Human. Er wurde validiert für IHC (p) und IHC (fro).

Kurzübersicht für AMACR Antikörper (ABIN115448)

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMACR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-AMACR Antikörper

Spezifität: Reacts to P504S Alpha-Methylacyl-CoA Racemace.
Cellular Localization: Cytoplasmic.

Aufreinigung: Purified

Immunogen: A synthetic human AMACR peptide.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: 1/25-1/50 in anABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Prostate carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu AMACR

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Andere Bezeichnung: AMACR / RACE

Hintergrund: P504S (AMARC) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.Synonyms: 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, P504S

Gen-ID: 23600

NCBI Accession: NP_055139

UniProt: Q9UHK6

Pathways: Monocarboxylic Acid Catabolic Process