IGF1 Antikörper

Produktnummer ABIN111026

Der Maus Monoklonal Anti-IGF1 Antikörper wurde für RIA, EIA und IHC (fro) validiert. Er ist geeignet, IGF1 in Proben von Human zu detektieren.

Kurzübersicht für IGF1 Antikörper (ABIN111026)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGF1 Antikörper ist unkonjugiert

Applikation: Radioimmunoassay (RIA), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: BM23

Produktdetails anti-IGF1 Antikörper

Spezifität: The basic IGF-1-like forms (pI>9.0) showed substantial cross-reactivity, as did Rat and Mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in-vitro bioassays for insulin-like, mitogenic and sulphation activities. Cross-reactivity: ILGF-1:100 % ILGF-2:1 % Proinsulin: 1.4 % MSF: 1 % Insulin: < 0.1 %.Aff. Const.:10e8-10e9 l/mole

Aufreinigung: Affinity Chromatography on Protein A.

Immunogen: Purified human IGF-1 conjugated to ovalbumin.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: RIA. ELISA. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS buffer with 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Andere Bezeichnung: Insulin-Like Growth Factor I / IGF1

Hintergrund: Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.Synonyms: IBP1, IGF-I, MGF, Mechano growth factor, Somatomedin-C

Gen-ID: 3479

NCBI Accession: NP_000609

UniProt: P05019

Pathways: RTK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation