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RPS6KB1 Antikörper

RPS6KB1 Reaktivität: Human WB, IHC (p), FACS, EIA Wirt: Maus Monoclonal 5G9 unconjugated
Produktnummer ABIN1108904
  • Target Alle RPS6KB1 Antikörper anzeigen
    RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
    Reaktivität
    • 321
    • 230
    • 228
    • 55
    • 23
    • 21
    • 20
    • 17
    • 12
    • 9
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 304
    • 33
    • 2
    • 2
    Maus
    Klonalität
    • 308
    • 34
    Monoklonal
    Konjugat
    • 163
    • 19
    • 16
    • 14
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    Dieser RPS6KB1 Antikörper ist unkonjugiert
    Applikation
    • 277
    • 131
    • 104
    • 94
    • 91
    • 73
    • 59
    • 30
    • 24
    • 18
    • 17
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes RPS6KB1 / STK14A
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Purified
    Klon
    5G9
    Isotyp
    IgG1
    Top Product
    Discover our top product RPS6KB1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
    Andere Bezeichnung
    RPS6KB1 / STK14A (RPS6KB1 Produkte)
    Hintergrund
    This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.Synonyms: 70 kDa ribosomal protein S6 kinase 1, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, Serine/threonine-protein kinase 14A, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K 1
    Molekulargewicht
    59 kDa
    Gen-ID
    6198
    Pathways
    PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effekt
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