TLR4 Antikörper (FITC)
-
- Target Alle TLR4 Antikörper anzeigen
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser TLR4 Antikörper ist konjugiert mit FITC
-
Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein G
- Immunogen
- CHO cells expressing chimeric human TLR4/MD-2 fusion protein
- Klon
- 3C3
- Isotyp
- IgG1
- Top Product
- Discover our top product TLR4 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 1 % bovine serum albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C.
-
- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Andere Bezeichnung
- CD284 / TLR4 (TLR4 Produkte)
- Hintergrund
- TLRs belong to a family of proteins that specifically recognize and sense microbial products. They are highly conserved throughout evolution. In Drosophila, toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. TLRs identified as type I transmembrane signalling receptors act as innate immune recognition receptors against many pathogens.TLR4 is a functional receptor for gram-negative bacterial lipopolysaccharides (LPS). TLR4 associates with MD-2 which is absolutely required for LPS-induced activation of TLR4. TLR4 has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to LPS of Gram-negative bacteria.Synonyms: Toll-like receptor 4
- NCBI Accession
- NM_138554
- UniProt
- O00206
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine
-