PSMD14 Antikörper

Produktnummer ABIN108606

Zitiert in 3+ Publikationen. Der Maus Monoklonal anti-PSMD14 Antikörper (Klon 9B10) (ABIN108606) detektiert spezifisch PSMD14 in IF, ICC, IP und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PSMD14 Antikörper (ABIN108606)

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PSMD14 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS)

Klon: 9B10

Produktdetails anti-PSMD14 Antikörper

Aufreinigung: Protein A

Immunogen: Recombinant full length Mad1 protein (human)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however as a guideline try, IF: 1/500 - 1/1000. IP: Use at a concentration of 5 μg/0.5 - 1 mL of extract. 

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.9 mg/mL

Buffer: Purified antibody containing PBS 0.1 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Referenzen für anti-PSMD14 Antikörper (ABIN108606)

Sartorius, DApice, Trovato, Cuccaro, Costa, De Leo, Marzullo, Biondo, DAuria, De Matteis, Ciccodicola, De Berardinis: "Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response." in: EMBO molecular medicine, Vol. 7, Issue 7, pp. 973-88, (2015) (PubMed).

Hewitt, Tighe, Santaguida, White, Jones, Musacchio, Green, Taylor: "Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex." in: The Journal of cell biology, Vol. 190, Issue 1, pp. 25-34, (2010) (PubMed).

Weaver, Bonday, Putkey, Kops, Silk, Cleveland: "Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss." in: The Journal of cell biology, Vol. 162, Issue 4, pp. 551-63, (2003) (PubMed).

Details zu PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Andere Bezeichnung: Mad1

Hintergrund: Synonyms:
hMAD1 antibody,HsMAD1 antibody,MAD-1 antibody,MAD1L1 antibody,Mitotic arrest deficient 1antibody,Mitotic checkpoint MAD1 protein homolog antibody,Mitotic spindle assembly checkpoint protein MAD1antibody,PIG-9 antibody,PIG9 antibody,Tax binding protein 181 antibody,TP53I9 antibody,Tumor protein p53inducible protein 9 antibody,TXBP181 antibody

Gen-ID: 296137

OMIM: 602686

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway