anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) Antikörper

CACNA2D3 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Zusätzlich bieten wir Ihnen CACNA2D3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CACNA2D3 55799 Q8IZS8
CACNA2D3 12294 Q9Z1L5
CACNA2D3 306243 Q8CFG5
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Showing 10 out of 35 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, FACS, WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
$517.00
Details
Human Kaninchen Unkonjugiert FACS, WB Western blot analysis of CACNA2D3 Antibody (C-term) (ABIN653695) in HepG2 cell line lysates (35 µg/lane). CACNA2D3 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extract of various cells, using CACNA2D3 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.77
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Human Kaninchen Unkonjugiert IHC (fro), IHC (p), IHC, WB   0.5 mg Anmelden zum Anzeigen 12 bis 15 Tage
$444.19
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Human Kaninchen Unkonjugiert IHC, WB   500 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
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Human Kaninchen Unkonjugiert FACS, ELISA, WB   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
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Human Kaninchen HRP FACS, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
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Human Kaninchen PE FACS, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
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Human Kaninchen APC FACS, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
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Human Kaninchen Biotin FACS, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

Weitere Antikörper gegen CACNA2D3 Interaktionspartner

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) Interaktionspartner

  1. Nine of the 32 (28.1%) iCCA (zeige PRRT2 Antikörper) patients had gene mutations at chromosome 3p, totaling 11 mutations across five genes. Those included five (15.6%) BAP1 (zeige RNF2 Antikörper) mutations, two each (6.3%) of CACNA2D3 and RASSF1 (zeige RASSF1 Antikörper) mutations, and one each (3.1%) of ATG7 (zeige ATG7 Antikörper) and PLCD1 (zeige PLCD1 Antikörper) mutations. Six (18.8%) cases had concurrent loss of chromosome 3p and gene mutations.

  2. Findings demonstrate the tumor suppressive role of CACNA2D3 in gliomas. CACNA2D3 operates via Ca 2thorn signaling and the activation of non-canonical Wnt (zeige WNT2 Antikörper) signaling to inhibit cell proliferation and motility and induce apoptosis.

  3. The risk of developing anaemia is increased in reproductive age women carriers of A allele of rs1868505 (CACNA2D3) and/or T allele of rs13194491 (HIST1H2BJ).

  4. CACNA2D3-mediated increase in intracellular calcium (Ca2 (zeige CA2 Antikörper)+) can induce mitochondrial-mediated apoptosis.

  5. CACNA2D3 is a novel tumor suppressor gene responsible for the 3p21 deletion event that plays a critical suppressing role in the development and progression of esophageal squamous cell carcinoma.

  6. CACNA2D3 polymorphism rs1375515 plays important role in iron status and is associated with the levels of iron-related biomarkers, as well as with iron clinical phenotypes (normal, iron de fi cient and anaemic).

  7. Expression of CACNA2D3 mRNA is regulated in breast cancer cell lines by methylation in the CpG island located in the 5' regulatory region of the gene.

  8. High CACNA2D3 gene expression is assiciated with glioblastoma multiforme.

  9. In humans, study found single-nucleotide polymorphisms in alpha2delta3 that are associated with reduced acute heat pain sensitivity in healthy volunteers and chronic postsurgical back pain.

  10. did not detect submicroscopic deletion or duplication nor sequence alteration in either CACNA2D3 or WNT5A (zeige WNT5A Antikörper) in ZLS-affected individuals

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) Interaktionspartner

  1. our results identify a novel role for the alpha2delta3 auxiliary subunit in the structure and function of specific synapses in the mammalian auditory pathway and in auditory processing disorders.

  2. Mice mutant for the stj ortholog CACNA2D3 (alpha2delta3) exhibit impaired behavioral heat pain sensitivity.

CACNA2D3 Antigen-Profil

Protein Überblick

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Genbezeichner und Symbole assoziert mit CACNA2D3

  • calcium voltage-gated channel auxiliary subunit alpha2delta 3 (CACNA2D3) Antikörper
  • calcium channel, voltage dependent, alpha2/delta subunit 3 (cacna2d3) Antikörper
  • calcium channel, voltage-dependent, alpha2/delta subunit 3 (Cacna2d3) Antikörper
  • calcium voltage-gated channel auxiliary subunit alpha2delta 3 (Cacna2d3) Antikörper
  • Cacnad3 Antikörper
  • HSA272268 Antikörper

Bezeichner auf Proteinebene für CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta 3 subunit , voltage-dependent calcium channel subunit alpha-2/delta-3 , calcium channel, voltage-dependent, alpha 2/delta subunit 3 , calcium channel, voltage-dependent, alpha 2/delta 3 subunit-like , voltage-dependent calcium channel subunit alpha-2/delta-3-like , calcium channel alpha2-delta3 subunit , voltage-gated calcium channel subunit alpha-2/delta-3 , alpha 2 delta-3 , alpha2delta3 , calcium channel, voltage dependent, alpha2/delta subunit 3

GENE ID SPEZIES
415996 Gallus gallus
460457 Pan troglodytes
476585 Canis lupus familiaris
519644 Bos taurus
100148645 Danio rerio
100400467 Callithrix jacchus
100448999 Pongo abelii
55799 Homo sapiens
12294 Mus musculus
306243 Rattus norvegicus
Ausgewählte Anbieter für anti-CACNA2D3 (CACNA2D3) Antikörper
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