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Rat (Rattus) CTNNB1 ELISA Kit für Sandwich ELISA - ABIN431880
Shao, Cai, Sheng, Yin: Role of SDF-1 and Wnt signaling pathway in the myocardial fibrosis of hypertensive rats. in American journal of translational research 2015
Human CTNNB1 ELISA Kit für Sandwich ELISA - ABIN416829
Gupta, Khan, Kumar, Kumar, Sharma: Versican and its associated molecules: potential diagnostic markers for multiple myeloma. in Clinica chimica acta; international journal of clinical chemistry 2015
Mouse (Murine) CTNNB1 ELISA Kit für Sandwich ELISA - ABIN424163
Chen, Feng, Bao, Li, Zhang, Shen, Zhao, Guo, Jing, Lin, Zong: Adverse Effects of Osteocytic Constitutive Activation of ß-Catenin on Bone Strength and Bone Growth. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015
Human CTNNB1 ELISA Kit für Sandwich ELISA - ABIN832441
Gaudio, Privitera, Battaglia, Torrisi, Sidoti, Pulvirenti, Canzonieri, Tringali, Fiore: Sclerostin levels associated with inhibition of the Wnt/?-catenin signaling and reduced bone turnover in type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2012
temporal expression of CTNNB1 mRNA during dermal wound repair in the horse
Transcriptional cofactors Bcl9 (zeige BCL9 ELISA Kits), Bcl9l (zeige BCL9L ELISA Kits) and Pygo1/2 act independently of beta-catenin to ensure proper enamel formation.
Transient expression of WNT2 (zeige WNT2 ELISA Kits) promotes somatic cell reprogramming by inducing beta-catenin nuclear accumulation.
Beta-catenin regulates expression of downstream targets of a key transcriptional memory gene, Hoxa9 (zeige HOXA9 ELISA Kits) that is highly enriched in myeloid leukemia (zeige BCL11A ELISA Kits) cancer stem cells and helps sustain leukemic self-renewal.
Under diabetic oxidative stress or H2O2 stimulation, nuclear beta-catenin accumulation upregulated downstream c-Myc (zeige MYC ELISA Kits) and further facilitated DNA damage and p53 (zeige TP53 ELISA Kits)-mediated apoptosis as well as cell viability reduction, followed by phenotypic changes of cardiac dysfunction, interstitial fibrosis deposition and myocardial atrophy.
direct overexpression of Foxl2 (zeige FOXL2 ELISA Kits) decreased the expression of Sertoli cell-specific genes in primary Sertoli cells. Taken together, these results demonstrate that repression of beta-catenin (CTNNB1) signaling is required for lineage maintenance of Sertoli cells.
Results demonstrate a new mechanism for the modulation of synapse formation, whereby MET activation induces an alignment of presynaptic and postsynaptic elements that are necessary for assembly and formation of functional synapses by subsets of neocortical neurons that express MET/beta-catenin complex.
Following transepithelial migration, neutrophils adhesion to ICAM-1 (zeige ICAM1 ELISA Kits) resulted in activation of Akt (zeige AKT1 ELISA Kits) and beta-catenin signaling, increased epithelial-cell proliferation, and wound healing.
receptor for advanced glycation end products (RAGE (zeige AGER ELISA Kits)) was required for stabilization of beta-catenin in toluene diisocyanate-induced asthma, identifying protective effects of RAGE (zeige AGER ELISA Kits) blockade in this mouse model
Axud1 mediated stress-induced cardiomyocytes apoptosis through activating Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling pathway.
Our findings are consistent with published reports wherein anterior taste buds have higher sweet sensitivity while posterior taste buds are better tuned to bitter, and suggest beta-catenin plays a greater role in renewal of anterior versus posterior taste buds.
Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling induces expression of col12a1a/b and deposition of Collagen XII, which is necessary for axons to actively navigate the non-neural lesion site environment.
Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.
Nuclear beta-catenin is an indication of an activated Wnt (zeige WNT2 ELISA Kits) pathway, therefore suggesting a possible role for Wnt (zeige WNT2 ELISA Kits) signalling during zebrafish tooth development and replacement.
Findings suggest that microRNA 19b (miR (zeige MYLIP ELISA Kits)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.
Custos binds to beta-catenin in a Wnt (zeige WNT2 ELISA Kits) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.
The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.
The Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)
This study demonstrated that beta-catenin/Wnt (zeige WNT2 ELISA Kits) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (zeige WNT2 ELISA Kits) signaling subsequently controls the fate of the progeny of those cell divisions.
A novel role for Eaf1 and Eaf2 (zeige EAF2 ELISA Kits) in inhibiting canonical Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 (zeige EAF2 ELISA Kits) tumor suppressor activity.
Ccr7 (zeige CCR7 ELISA Kits) functions during axis formation as a GPCR (zeige GPRC6A ELISA Kits) to inhibit beta-catenin, likely by promoting Ca(2 (zeige CA2 ELISA Kits)+) transients throughout the blastula.
Together, these results indicate that capsaicin inhibits the patterning of the dorso-ventral and anterior-posterior body axes of embryo by repressing PP2A and thereby down-regulating the Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling.
maternal Wnt (zeige WNT2 ELISA Kits)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression
Wnt (zeige WNT2 ELISA Kits) signalling can benefit from nucleo-cytoplasmic shuttling of APC (zeige APC ELISA Kits), Axin (zeige AXIN1 ELISA Kits) and GSK3 (zeige GSK3b ELISA Kits), although they are in general beta-catenin antagonising proteins.
Phosphoinositide 3-kinase and Rac (zeige AKT1 ELISA Kits) polarization depend specifically on the N-cadherin (zeige CDH2 ELISA Kits)-p120 catenin (zeige CTNND1 ELISA Kits) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (zeige CDH2 ELISA Kits)-beta-catenin complex.
HERG (zeige KCNH2 ELISA Kits) channel activity is stimulated by beta-catenin
Zic3 (zeige ZIC3 ELISA Kits) can suppress Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling and control development of the notochord and Spemann's organizer.
Notch (zeige NOTCH1 ELISA Kits) initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 (zeige GSK3b ELISA Kits)
The tyrosine kinase receptor (zeige KDR ELISA Kits), PTK7 (zeige PTK7 ELISA Kits), is implicated in beta-catenin-dependent developmental processes.
Kazrin (zeige KAZ ELISA Kits) interacts with ARVCF (zeige ARVCF ELISA Kits)-catenin, spectrin and p190B (zeige ARHGAP5 ELISA Kits) RhoGAP (zeige ARHGAP1 ELISA Kits), and modulates RhoA (zeige RHOA ELISA Kits) activity.
In conclusion, we report a patient with a known CTNNB1 mutation causing the familial exudative vitreoretinopathy (FEVR (zeige NDP ELISA Kits)) phenotype.
Knockdown of GATA6 (zeige GATA6 ELISA Kits) completely eliminated the effect of TCF1 (zeige HNF1A ELISA Kits), while forced expression of GATA6 (zeige GATA6 ELISA Kits) induced hESC differentiation
High CTNNB1 expression is associated with prostate cancer.
We propose a novel role of the miR (zeige MLXIP ELISA Kits)-27a/PPARgamma (zeige PPARG ELISA Kits)/beta-catenin axis in fostering the progression toward more deteriorated podocyte injury in diabetic nephropathy (DN). Targeting miR (zeige MLXIP ELISA Kits)-27a could be a potential therapeutic approach for DN.
High beta catenin expression in stromal cells is associated with myelodysplastic syndrome.
Meta-analysis revealed an increase in CTNNB1 and a decrease in DICER1 (zeige DICER1 ELISA Kits) expression levels in the high-risk group. These results uncover beta-catenin as a critical factor in promoting ovarian cancer aggressiveness and a new mechanism linking between beta-catenin and miRNA downregulation underlying this process
Studies indicate that the small molecule ICG-001 selectively blocks the cAMP response element-binding (CREB (zeige CREB1 ELISA Kits)) protein (CBP (zeige CREBBP ELISA Kits))/beta-catenin or gamma-catenin (zeige JUP ELISA Kits) interaction.
Expression of MUCDHL (zeige CDHR5 ELISA Kits) is negatively regulated by the activation of the beta-catenin signaling pathway in normal and cancer colorectal enterocytes.
These results suggest RAI3 (zeige GPRC5A ELISA Kits) plays an important role in adipogenesis of hASCs and may have a potential use in the future application.
Results highlight a potential role for the beta-catenin/Wnt (zeige WNT2 ELISA Kits) and Notch (zeige NOTCH1 ELISA Kits) signalling pathways during the infection of crypt cells by L. intracellularis.
Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.
beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.
Wnt3a (zeige WNT3A ELISA Kits) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.
beta-catenin controls myocardin (zeige MYOCD ELISA Kits)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes
beta-Catenin plays a critical role in mediating TGF-beta1 (zeige TGFB1 ELISA Kits)-induced myofibroblast differentiation in aortic valve interstitial cells.
scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin
Data show that Wnt3a (zeige WNT3A ELISA Kits) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.
TNF-alpha (zeige TNF ELISA Kits) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.
Bovine herpesvirus 1 transiently increased beta-catenin protein levels in bovine kidney cells, but not in rabbit skin cells.
These results demonstrate that activation of AKT (zeige AKT1 ELISA Kits) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.
beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.
These data demonstrate for the first time that FSH (zeige BRD2 ELISA Kits) regulates CTNNB1 protein and WNT2 (zeige WNT2 ELISA Kits) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (zeige WNT2 ELISA Kits) signaling in ovarian steroidogenesis and follicular growth of cattle.
These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.
that beta-catenin is a plasma membrane-associated protein (zeige PDZK1IP1 ELISA Kits) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.
This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.
TGF-beta3 (zeige TGFB3 ELISA Kits) induces the chondrogenic differentiation of pericytes by inducing Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling and T-cell factor-induced gene transcription.
cAMP/PKA regulation of GSK3beta (zeige GSK3b ELISA Kits)/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.
Palmatin effect on osteoarthritis is likely mediated via the Wnt (zeige WNT2 ELISA Kits)/beta-catenin and Hedgehog (zeige SHH ELISA Kits) signaling
These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
catenin beta 1 subunit
, catenin beta-1
, beta catenin 1
, catenin (cadherin-associated protein), beta 1, 88kDa
, catenin beta-1-like
, catenin (cadherin associated protein), beta 1, 88kDa
, catenin beta
, beta catenin