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Human CTNNB1 ELISA Kit für Sandwich ELISA - ABIN832441
Gaudio, Privitera, Battaglia, Torrisi, Sidoti, Pulvirenti, Canzonieri, Tringali, Fiore: Sclerostin levels associated with inhibition of the Wnt/?-catenin signaling and reduced bone turnover in type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2012
Rat (Rattus) CTNNB1 ELISA Kit für Sandwich ELISA - ABIN431880
Shao, Cai, Sheng, Yin: Role of SDF-1 and Wnt signaling pathway in the myocardial fibrosis of hypertensive rats. in American journal of translational research 2015
Mouse (Murine) CTNNB1 ELISA Kit für Sandwich ELISA - ABIN424163
Chen, Feng, Bao, Li, Zhang, Shen, Zhao, Guo, Jing, Lin, Zong: Adverse Effects of Osteocytic Constitutive Activation of ß-Catenin on Bone Strength and Bone Growth. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015
temporal expression of CTNNB1 mRNA during dermal wound repair in the horse
TIEG1 is involved in regulating the canonical Wnt (zeige WNT2 ELISA Kits) signaling pathway in bone through multiple mechanisms of action.
Activation of WNT/b-catenin activity improved cardiac contractility and ameliorated intraventricular conduction defects in LmnaH222P/H222P mice, which was associated with increased expression of myocardial connexin 43. These results indicate that decreased WNT/b-catenin contributes to the pathophysiology of LMNA cardiomyopathy and that drugs activating b-catenin may be beneficial in affected individuals
Oncogenic beta-catenin and PI3K activities interact in the acquisition of multiple cancer-related phenotypes in organoids grown in Matrigel.
We further found that knockdown of Kif2a (zeige KIF2A ELISA Kits) decreased the protein level of b-catenin, which is a critical molecule for neocortical neurogenesis. Together, these results reveal an important function of Kif2a (zeige KIF2A ELISA Kits) in embryonic neocortical neurogenesis
Data show that both Wnt1 (zeige WNT1 ELISA Kits)-cre and P0-cre are similarly effective in deleting beta-catenin in the neural crest.
HIRA (zeige HIRA ELISA Kits), in cooperation with Setd1A (zeige SETD1A ELISA Kits), modulates beta-catenin expression to regulate neural stem cell proliferation and neurogenesis.
Wnt/beta-catenin signaling via Axin2 is required for myogenesis and, together with YAP/Taz and Tead1, active in IIa/IIx muscle fibers
cadherin 2 (CDH2 (zeige CDH2 ELISA Kits)) and CDH4 (zeige CDH4 ELISA Kits) cooperate to regulate radial migration in mouse brain via the protein tyrosine phosphatase 1B (PTP1B (zeige PTPN1 ELISA Kits)) and alpha- and beta-catenins.
Postnatal beta-catenin ablation in fibroblasts promoted hair follicle (HF) regeneration in neonatal and adult mouse wounds, whereas beta-catenin activation reduced HF regeneration in neonatal wounds.
In the absence of the zona pellucida, embryos lacking CTNNB1 undergo fission and these separated blastomeres can become small trophoblastic vesicles, which in turn induce decidual reactions.
Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.
Nuclear beta-catenin is an indication of an activated Wnt (zeige WNT2 ELISA Kits) pathway, therefore suggesting a possible role for Wnt (zeige WNT2 ELISA Kits) signalling during zebrafish tooth development and replacement.
Findings suggest that microRNA 19b (miR (zeige MYLIP ELISA Kits)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.
Custos binds to beta-catenin in a Wnt (zeige WNT2 ELISA Kits) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.
The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.
The Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)
This study demonstrated that beta-catenin/Wnt (zeige WNT2 ELISA Kits) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (zeige WNT2 ELISA Kits) signaling subsequently controls the fate of the progeny of those cell divisions.
A novel role for Eaf1 and Eaf2 (zeige EAF2 ELISA Kits) in inhibiting canonical Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 (zeige EAF2 ELISA Kits) tumor suppressor activity.
Ccr7 (zeige CCR7 ELISA Kits) functions during axis formation as a GPCR (zeige GPRC6A ELISA Kits) to inhibit beta-catenin, likely by promoting Ca(2 (zeige CA2 ELISA Kits)+) transients throughout the blastula.
ctnnb1 and ctnnb2 regulate multiple processes of laterality development in zebrafish embryos through similar and distinct mechanisms.
Together, these results indicate that capsaicin inhibits the patterning of the dorso-ventral and anterior-posterior body axes of embryo by repressing PP2A and thereby down-regulating the Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling.
maternal Wnt (zeige WNT2 ELISA Kits)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression
Wnt (zeige WNT2 ELISA Kits) signalling can benefit from nucleo-cytoplasmic shuttling of APC (zeige APC ELISA Kits), Axin (zeige AXIN1 ELISA Kits) and GSK3 (zeige GSK3b ELISA Kits), although they are in general beta-catenin antagonising proteins.
Phosphoinositide 3-kinase and Rac (zeige AKT1 ELISA Kits) polarization depend specifically on the N-cadherin (zeige CDH2 ELISA Kits)-p120 catenin (zeige CTNND1 ELISA Kits) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (zeige CDH2 ELISA Kits)-beta-catenin complex.
HERG (zeige KCNH2 ELISA Kits) channel activity is stimulated by beta-catenin
Zic3 (zeige ZIC3 ELISA Kits) can suppress Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling and control development of the notochord and Spemann's organizer.
Notch (zeige NOTCH1 ELISA Kits) initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 (zeige GSK3b ELISA Kits)
The tyrosine kinase receptor (zeige KDR ELISA Kits), PTK7 (zeige PTK7 ELISA Kits), is implicated in beta-catenin-dependent developmental processes.
Kazrin (zeige KAZ ELISA Kits) interacts with ARVCF (zeige ARVCF ELISA Kits)-catenin, spectrin and p190B (zeige ARHGAP5 ELISA Kits) RhoGAP (zeige ARHGAP1 ELISA Kits), and modulates RhoA (zeige RHOA ELISA Kits) activity.
our findings identify the miR (zeige MLXIP ELISA Kits)-410/Gsk3beta (zeige GSK3b ELISA Kits)/beta-catenin signaling axis is a novel molecular circuit in inducing stemness of non-small cells lung cancer
NOR1 (zeige NR4A3 ELISA Kits) suppresses cancer stem-like cell properties in nasopharyngeal carcinoma cells by inhibiting the AKT (zeige AKT1 ELISA Kits)-GSK-3beta (zeige GSK3b ELISA Kits)-Wnt (zeige WNT2 ELISA Kits)/beta-catenin-ALDH1A1 (zeige ALDH1A1 ELISA Kits) signaling circuit.
Data suggest that DBC1 (zeige DBC1 ELISA Kits) has a dual function in regulating beta-catenin-PROX1 (zeige PROX1 ELISA Kits) signaling axis: as a coactivator for both beta-catenin and PROX1 (zeige PROX1 ELISA Kits).
Indicate that beta-catenin and SATB2 (zeige SATB2 ELISA Kits) are useful immunohistochemical markers for differentiating between pulmonary enteric adenocarcinoma and metastatic colorectal carcinoma.
In promoting the self-renewal symmetric division of hTERT(high) prostate cancer cells, WNT3a (zeige WNT3A ELISA Kits) dramatically decreased the ratio of hTERT(high) prostate cancer cells undergoing asymmetric division. Increased WNT (zeige WNT2 ELISA Kits)/beta-catenin signal activation was also detected in hTERT(high) prostate cancer cells. hTERT-mediated CSC properties were at least partially dependent on beta-catenin.
These data define the mechanism responsible for the repressive effects of nitric oxide (NO) on the transcriptional activity of beta-catenin and link eNOS (zeige NOS3 ELISA Kits)-derived NO to the modulation by VEGF (zeige VEGFA ELISA Kits) of Wnt (zeige WNT2 ELISA Kits)/beta-catenin-induced endothelial cell proliferation.
Mutation in CTNNB1 gene is associated with Pancreatic Ductal Adenocarcinoma.
Lung allografts in bronchiolitis obliterans syndrome, demonstrated reduced beta-catenin transcriptional activation in the presence of LPA1 (zeige LPAR1 ELISA Kits) antagonist, confirming an in vivo role for lysophosphatidic acid signaling in beta-catenin activation.
beta-catenin is a key mediator of P. falciparum adverse effects on endothelial integrity.
GLI2 (zeige GLI2 ELISA Kits) is a regulator of beta-catenin and provides insights into its role in tumorigenesis.
Results highlight a potential role for the beta-catenin/Wnt (zeige WNT2 ELISA Kits) and Notch (zeige NOTCH1 ELISA Kits) signalling pathways during the infection of crypt cells by L. intracellularis.
Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.
beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.
Wnt3a (zeige WNT3A ELISA Kits) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.
beta-catenin controls myocardin (zeige MYOCD ELISA Kits)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes
beta-Catenin plays a critical role in mediating TGF-beta1 (zeige TGFB1 ELISA Kits)-induced myofibroblast differentiation in aortic valve interstitial cells.
scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin
Data show that Wnt3a (zeige WNT3A ELISA Kits) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.
TNF-alpha (zeige TNF ELISA Kits) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.
Bovine herpesvirus 1 transiently increased beta-catenin protein levels in bovine kidney cells, but not in rabbit skin cells.
These results demonstrate that activation of AKT (zeige AKT1 ELISA Kits) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.
beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.
These data demonstrate for the first time that FSH (zeige BRD2 ELISA Kits) regulates CTNNB1 protein and WNT2 (zeige WNT2 ELISA Kits) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (zeige WNT2 ELISA Kits) signaling in ovarian steroidogenesis and follicular growth of cattle.
These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.
that beta-catenin is a plasma membrane-associated protein (zeige PDZK1IP1 ELISA Kits) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.
This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.
TGF-beta3 (zeige TGFB3 ELISA Kits) induces the chondrogenic differentiation of pericytes by inducing Wnt (zeige WNT2 ELISA Kits)/beta-catenin signaling and T-cell factor-induced gene transcription.
cAMP/PKA regulation of GSK3beta (zeige GSK3b ELISA Kits)/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.
Palmatin effect on osteoarthritis is likely mediated via the Wnt (zeige WNT2 ELISA Kits)/beta-catenin and Hedgehog (zeige SHH ELISA Kits) signaling
These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
catenin beta 1 subunit
, catenin beta-1
, beta catenin 1
, catenin (cadherin-associated protein), beta 1, 88kDa
, catenin beta-1-like
, catenin (cadherin associated protein), beta 1, 88kDa
, catenin beta
, beta catenin