anti-TLR2 (TLR2) Antikörper

Bezeichnung:
anti-Toll-Like Receptor 2 Antikörper (TLR2)
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Synonyme:
CD282, Ly105, TIL4, TLR2, TLR2B
Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human TLR2 TLR2 7097 O60603
Anti-Maus TLR2 TLR2 24088 Q9QUN7
Anti-Ratte TLR2 TLR2 310553  

Weitere Synonyme anzeigen

Weitere Antikörper gegen TLR2 Interaktionspartner

Human Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. two functional relevant polymorphisms in TLR2, the GTn (zeige GNAT3 Antikörper) microsatellite repeat polymorphism in intron 2 and the Arg753Gln variant do not seem to play a role in the susceptibility to Crohn's disease or ulcerative colitis

  2. IgG (mAb)-opsonized, inactivated Francisella tularensis LVS enhances macrophage and dendritic cell IL-1beta (zeige IL1B Antikörper) responses in a TLR2- and FcgammaR-dependent fashion.

  3. Estradiol alters the immune-responsiveness of cultured HECECs to TLR2 and TLR4 (zeige TLR4 Antikörper) ligands in a complex fashion that appears to vary with bacterial ligand, TLR subtype, and duration of exposure

  4. Among various TLR2, TLR4 (zeige TLR4 Antikörper) and TLR9 (zeige TLR9 Antikörper) polymorphisms, TLR2 2258 G/A single nucleotide polymorphism seems to be an important factor associated with increased risk of congenital human cytomegalovirus infection in Polish fetuses and neonates.

  5. these findings identify new compounds for antagonizing TLR2 and TLR4 (zeige TLR4 Antikörper) activation and define structural properties of POPG analogs for discriminating between two TLR systems.

  6. results indicate that rhinovirus (RV) stimulates CXCL-10 (zeige CXCL10 Antikörper) expression via the IL-33 (zeige IL33 Antikörper)/ST2 (zeige SULT2A1 Antikörper) signaling axis, and that TLR2 signaling limits RV-induced CXCL-10 (zeige CXCL10 Antikörper) via IRAK-1 (zeige IRAK1 Antikörper) depletion at least in airway epithelial cells

  7. The combination of glucocorticosteroids with TLR ligands can increase TLR2 expression in alveolar macrophages, thereby improving host defense in smokers.

  8. TLR2 polymorphism may contribute to the pathogenesis of AMD (zeige AMD1 Antikörper).

  9. The mRNA levels of Toll (zeige TLR4 Antikörper)-like receptors TLR2, 6, and 9 were significantly elevated in the Kawasaki disease (KD) patient group versus the healthy controls.

  10. TLR2 signaling is very likely impaired in patients with fulminant form of hepatitis B-related acute liver failure. The recurrence of rare case-specific TLR2 variant strongly suggests mechanistic contribution to fulminancy in HBV infection.

Mouse (Murine) Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. Dual TLR2/TLR7 (zeige TLR7 Antikörper) agonist induced the maturation of dendritic cells and primed substantial populations of cytolytic and highly polyfunctional effector CD8 (zeige CD8A Antikörper)(+) T cells in vitro, and safely potentiated the immunogenic properties of a nanoparticulate Ag in vivo, eliciting humoral responses with a balanced TH1 (zeige HAND1 Antikörper)/TH2 profile in mice.

  2. In conclusion, the authors demonstrate that TLR2 diminishes the development of adaptive immune responses during experimental deep dermatophytosis and, in a diabetic scenario, acts to intensify a non-protective inflammatory response.

  3. These findings indicate that TLR2 and TLR4 (zeige TLR4 Antikörper) are required to control Brucella microti infection in mice and that this effect could be related to its participation in the maturation of dendritic cells and the generation of specific CD8 (zeige CD8A Antikörper)(+) Tc cells.

  4. The results indicate that the disease-preventing effects of Bacteroides fragilis in acute dextran sulfate sodium-induced colitis may occur through the TLR2/IL-10 (zeige IL10 Antikörper) signal pathway.

  5. Silencing of TLR2 by siRNA substantially down-regulated MG-triggered autophagy in macrophages.

  6. we demonstrated for the first time that the cross-talk of TLR2 and TLR9 (zeige TLR9 Antikörper) triggered Th1 (zeige HAND1 Antikörper) activation collaboratively

  7. IgG (mAb)-opsonized, inactivated Francisella tularensis LVS enhances macrophage and dendritic cell IL-1beta (zeige IL1B Antikörper) responses in a TLR2- and FcgammaR-dependent fashion.

  8. a specific TLR2-mediated mechanism of central nervous system inflammation and leukocyte invasion into the neonatal brain, is reported.

  9. TLR2 signaling contributes to superficial erosion in the vascular endothelium and local blood flow disturbance.

  10. the cooperative role of TLR9 (zeige TLR9 Antikörper) with TLR2 or TLR6 (zeige TLR6 Antikörper) receptors in sensing Brucella, was determined.

Cow (Bovine) Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. results suggest that polymorphisms in the TLR2 gene might not play a significant role in the BTB risk in Chinese Holstein cattle

  2. Transcription levels of TLR2, TLR4 (zeige TLR4 Antikörper), and CD14 (zeige CD14 Antikörper) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.

  3. We structurally defined with 5'-RACE experiments three promoters (P1-3) controlling TLR2 expression in udder, liver and other tissues of cows suffering from E. coli mastitis.

  4. TLR2 and TLR4 (zeige TLR4 Antikörper) mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.

  5. positive correlation between lower neutrophil apoptosis and higher expression of TLR2 and TLR4 (zeige TLR4 Antikörper) with the formation of NETs and change in surface architecture.

  6. TLR2, TLR1 (zeige TLR1 Antikörper), and TLR6 (zeige TLR6 Antikörper) haev roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides by epithelial and stromal cells of bovine endometrium

  7. Data suggest that granulosa cells from dominant follicles express functional TLR2 and TLR4 (zeige TLR4 Antikörper); granulosa cells appear to participate in innate immunity by responding to bacterial lipopolysaccharides/lipopeptides via TLR2 and TLR4 (zeige TLR4 Antikörper) signaling pathways.

  8. The expressions of host TLR2 and 4 genes were significantly higher in acidosis-resistant steers compared to those in acidosis-susceptible steers.

  9. Whereas previous results regarding the TLR1 (zeige TLR1 Antikörper) gene were not corroborated, a risk haplotype was detected in TLR2; however, its low frequency indicates that this detected association should be interpreted with caution.

  10. The identification of antibodies specific for bovine and ovine TLR2 will facilitate studies of the role of this important pattern recognition receptors in the initiation of immune responses to important pathogens.

Rabbit Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. TLR2, 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.

  2. Lipopolysaccharide upregulates the expression of rabbit TLR2 and 4 in the uterine body and horn, and the expression of TLR4 (zeige TLR4 Antikörper) in the ovary.

  3. VB-201 may counter inflammation where TLR-2 and/or CD14 (zeige CD14 Antikörper) complicity is essential, and is therefore beneficial for the treatment of atherosclerosis.

Pig (Porcine) Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. Toll-like receptor 2 signaling on intestinal epithelial cells may enhance intestinal barrier function and prevent deoxynivalenol-induced barrier dysfunction of epithelial cells.

  2. These results suggest that porcine circovirus 2 induces IL-8 (zeige IL8 Antikörper) secretion via the TLR2/MyD88 (zeige MYD88 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signalling pathway.

  3. At 14 days after autotransplantation of a pig kidney, mRNA expression for TLR2 is increased.

  4. These data demonstrated that TLR2, TLR3 (zeige TLR3 Antikörper) and TLR9 (zeige TLR9 Antikörper) contribute to NF-kappaB (zeige NFKB1 Antikörper) activation in response to porcine epidemic diarrhea virus infection, but not RIG-I (zeige DDX58 Antikörper).

  5. Data suggest TLR2, TLR4 (zeige TLR4 Antikörper), and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2/TLR4 (zeige TLR4 Antikörper).

  6. TLR2 is required for the suppression of TLR4 (zeige TLR4 Antikörper) signaling activation.

  7. The role of TLR2, TLR4 (zeige TLR4 Antikörper) and RP105 (zeige CD180 Antikörper)/MD1 (zeige LY86 Antikörper) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (zeige CLPTM1 Antikörper), is reported.

  8. Single nucleotide polymorphisms in TLR2 is associated with immune response to gram-negative bacterial infections.

  9. The dramatic reduction in p38 MAPK (zeige MAPK14 Antikörper) phosphorylation by TLR-2 stimulation in aortic valve interstitial cells excludes a role for this receptor type in mediating angiotensin II or peroxynitrite effects.

  10. In total, 20, 27, and 26 SNPs were detected in TLR1 (zeige TLR1 Antikörper), TLR2, and TLR6 (zeige TLR6 Antikörper), respectively; in TLR1 (zeige TLR1 Antikörper) and TLR2, the numbers of SNPs detected were significantly lower (P < or = 0.05, P < or = 0.01) in the wild boars than in the domestic pigs.

Horse (Equine) Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. expression of TLR4 (zeige TLR4 Antikörper) and TLR2 in normal and LPS (zeige IRF6 Antikörper)-treated horses

Goat Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. Because factors other than mastitis can affect SCC (zeige CYP11A1 Antikörper) and our sample sizes were limited, additional studies are needed to corroborate an association between TLR2 genotype and SCC (zeige CYP11A1 Antikörper) or mastitis in goats.

  2. Over-expression of TLR2 decreases radical damage to host cells through low-level production of NO and MDA and promotes the clearance of invasive bacteria by up-regulating lysozyme (zeige LYZ Antikörper) secretion and filtration of inflammatory cells to the infected site.

Rhesus Monkey Toll-Like Receptor 2 (TLR2) Interaktionspartner

  1. TLR2 of M. fuscata has undergone purifying selection while the membrane-proximal part of the extracellular domain of M. mulatta TLR2 exhibits higher rates of non-synonymous substitutions, indicating a trace of Darwinian positive selection

  2. The results indicate that microglia and astrocytes respond to B (zeige TDO2 Antikörper). burgdorferi through TLR1 (zeige TLR1 Antikörper)/2 and TLR5 (zeige TLR5 Antikörper).

TLR2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Alternative names and synonyms associated with TLR2

  • toll-like receptor 2 (TLR2) Antikörper
  • toll-like receptor 2 (Tlr2) Antikörper
  • toll-like receptor 2 (TLR2-2) Antikörper
  • CD282 Antikörper
  • Ly105 Antikörper
  • TIL4 Antikörper
  • TLR2 Antikörper
  • TLR2B Antikörper

Bezeichner auf Proteinebene für TLR2

toll/interleukin 1 receptor-like 4 , toll/interleukin-1 receptor-like protein 4 , toll-like receptor 2 variant 1 , toll-like receptor 2 variant 2 , toll-like receptor 2 type-2 , toll-like receptor 2 type2 , Toll-like receptor 2-like protein

GENE ID SPEZIES
7097 Homo sapiens
24088 Mus musculus
281534 Bos taurus
310553 Rattus norvegicus
100717682 Cavia porcellus
100009578 Oryctolagus cuniculus
769014 Gallus gallus
448807 Canis lupus familiaris
396623 Sus scrofa
100009701 Equus caballus
554262 Ovis aries
100860747 Capra hircus
574290 Macaca mulatta
471325 Pan troglodytes
100994768 Pan paniscus
100689108 Cricetulus griseus
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