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anti-TAB1 (TAB1) Antikörper

Bezeichnung:
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 Antikörper (TAB1)
Auf www.antikoerper-online.de finden Sie aktuell 185 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TAB1 Proteine (7) und TAB1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 206 TAB1 Produkte verfügbar.
Synonyme:
3'-Tab1, 2310012M03Rik, b2b449Clo, Map3k7ip1

Meistgesuchte Reaktivitäten zu anti-TAB1 (TAB1) Antikörper

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anti-Human TAB1 Antikörper:

anti-Mouse (Murine) TAB1 Antikörper:

anti-Rat (Rattus) TAB1 Antikörper:

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Am meisten referenzierte anti-TAB1 Antikörper

  1. Human Monoclonal TAB1 Primary Antibody für WB - ABIN393632 : McGovern, Jones, Taylor, Marciante, Yan, Dubinsky, Ippoliti, Vasiliauskas, Berel, Derkowski, Dutridge, Fleshner, Shih, Melmed, Mengesha, King, Pressman, Haritunians, Guo, Targan, Rotter: Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. in Human molecular genetics 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN393632

  2. Human Monoclonal TAB1 Primary Antibody für IF, WB - ABIN393549 : Scholz, Sidler, Thali, Winssinger, Cheung, Neumann: Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN393549

  3. Human Polyclonal TAB1 Primary Antibody für EIA, WB - ABIN401658 : Arch, Gedrich, Thompson: Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death. in Genes & development 1998 (PubMed)
    Zeige alle 2 Referenzen für ABIN401658

  4. Human Polyclonal TAB1 Primary Antibody für EIA, WB - ABIN453175 : Yamaguchi, Nagai, Ninomiya-Tsuji, Nishita, Tamai, Irie, Ueno, Nishida, Shibuya, Matsumoto: XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. in The EMBO journal 1999 (PubMed)
    Zeige alle 2 Referenzen für ABIN453175

  5. Human Polyclonal TAB1 Primary Antibody für IF, IHC (p) - ABIN303281 : Shibuya, Yamaguchi, Shirakabe, Tonegawa, Gotoh, Ueno, Irie, Nishida, Matsumoto: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. in Science (New York, N.Y.) 1996 (PubMed)

  6. Chicken Polyclonal TAB1 Primary Antibody für WB - ABIN2785275 : Neil, Schiemann: Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression. in Cancer research 2008 (PubMed)

Weitere Antikörper gegen TAB1 Interaktionspartner

Human TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Interaktionspartner

  1. TAK1 (zeige MAP3K7 Antikörper)/TAB1 expression in non-small cell lung carcinoma tissue is significantly increased and closely associated with patient clinical prognosis.

  2. miR (zeige MLXIP Antikörper)-29a repressed TAB1-mediated TIMP-1 (zeige TIMP1 Antikörper) production in dermal fibroblasts, demonstrating that miR (zeige MLXIP Antikörper)-29a may be a therapeutic target in SSc (zeige CYP11A1 Antikörper).

  3. Data indicate that mitogen-activated protein kinase (zeige MAPK1 Antikörper) (MAPK) p38 (zeige MAPK1 Antikörper) activation is triggered by AMP (zeige APRT Antikörper)-activated protein kinases (AMPK (zeige PRKAA1 Antikörper)) and mediated by TAB1 protein.

  4. The amino acid sequence between positions 373 and 502 of TAB1 is required for TP interaction.

  5. USP18 (zeige USP18 Antikörper) inhibits NF-kappaB (zeige NFKB1 Antikörper) and NFAT (zeige NFATC1 Antikörper) activation during Th17 differentiation by deubiquitinating the TAK1 (zeige MAP3K7 Antikörper)-TAB1 complex.

  6. We found that endothelial TAK1 (zeige MAP3K7 Antikörper) and TAB2 (zeige TAB2 Antikörper), but not TAB1, were critically involved in vascular formation

  7. TAK1 (zeige MAP3K7 Antikörper) plays a critical role in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation.

  8. data suggest a complex role of aa 452-457 of TAB1 in controlling p38 MAPK (zeige MAPK14 Antikörper) activity and subcellular localization and implicate these residues in TAK1 (zeige MAP3K7 Antikörper)- or p38 MAPK (zeige MAPK14 Antikörper)-dependent post-transcriptional control of gene expression

  9. Phosphorylation and polyubiquitination of TAK1 (zeige MAP3K7 Antikörper) are necessary for activation of NF-kappaB (zeige NFKB1 Antikörper) by the Kaposi's sarcoma-associated herpesvirus vGPCR.

  10. Co-expression of TAK1 (zeige MAP3K7 Antikörper) and TAB1 resulted in a functional and active TAK1 (zeige MAP3K7 Antikörper)-TAB1 complex capable of directly activating full-length heterotrimeric mammalian AMP-activated protein kinase (AMPK (zeige PRKAA2 Antikörper)) in vitro.

Mouse (Murine) TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Interaktionspartner

  1. We confirmed that PGC (zeige PGC Antikörper)-1b inhibited downstream inflammatory signals via binding with TAB1 and thus preventing TAB1/TAK1 (zeige NR2C2 Antikörper) binding and TAK1 (zeige NR2C2 Antikörper) activation.

  2. The E3 ubiquitin ligase (zeige MUL1 Antikörper) Itch inhibits p38alpha (zeige MAPK14 Antikörper) signaling and skin inflammation through the ubiquitylation of Tab1.

  3. TAB1 and TAB2 (zeige TAB2 Antikörper) are required for activated macrophages, making TAB1 and TAB2 (zeige TAB2 Antikörper) effective targets to control inflammation by modulating macrophage survival.

  4. Both the MEKK1 (zeige MAP2K1 Antikörper) PHD (zeige PDC Antikörper) and TAB1 are critical for ES-cell differentiation

  5. The enhanced JNK (zeige MAPK8 Antikörper) and IkappaB kinase (zeige CHUK Antikörper) activation in DUSP14 (zeige DUSP14 Antikörper)-deficient T cells was attenuated by TAB1 short hairpin RNA knockdown.

  6. TAB1 binding stabilizes active p38alpha (zeige MAPK14 Antikörper) and induces rearrangements within the activation segment by helical extension of the Thr (zeige TRH Antikörper)-Gly-Tyr (zeige TYR Antikörper) motif, allowing autophosphorylation in cis (zeige CISH Antikörper)

  7. We found that endothelial TAK1 (zeige NR2C2 Antikörper) and TAB2 (zeige TAB2 Antikörper), but not TAB1, were critically involved in vascular formation

  8. O-GlcNAcylation of TAB1 is required for full TAK1 (zeige NR2C2 Antikörper) activation upon stimulation with IL-1 (zeige IL1A Antikörper)/osmotic stress.

  9. Epithelial TAK1 (zeige NR2C2 Antikörper) activity is regulated through two unique, TAB1-dependent basal & TAB2 (zeige TAB2 Antikörper)-mediated stimuli-dependent mechanisms.

  10. XIAP (zeige XIAP Antikörper)-TAB1-TAK1 (zeige NR2C2 Antikörper) complex is dependent on NRAGE (zeige MAGED1 Antikörper) for IKK-alpha (zeige CHUK Antikörper)/beta phosphorylation and NF-kappaB (zeige NFKB1 Antikörper) activation.

TAB1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with TAB1

  • TGF-beta activated kinase 1/MAP3K7 binding protein 1 (TAB1) Antikörper
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1) Antikörper
  • 3'-Tab1 Antikörper
  • 2310012M03Rik Antikörper
  • b2b449Clo Antikörper
  • Map3k7ip1 Antikörper

Bezeichner auf Proteinebene für TAB1

TAK1-binding protein 1 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 , mitogen-activated protein kinase kinase kinase 7-interacting protein 1 , transforming growth factor beta-activated kinase-binding protein 1 , TGF-beta-activated kinase 1-binding protein 1 , Tak1-binding protein 1 , beta activated kinase-1 binding protein-1 , mitogen activated protein kinase kinase kinase 7 interacting protein 1 , mitogen-activated protein kinase kinase kinase 7 interacting protein 1

GENE ID SPEZIES
10454 Homo sapiens
66513 Mus musculus
315139 Rattus norvegicus
100358246 Oryctolagus cuniculus
418014 Gallus gallus
481245 Canis lupus familiaris
519958 Bos taurus
100153785 Sus scrofa
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