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SR-B1 (zeige SCARB1 ELISA Kits) is a silica receptor associated with canonical inflammasome activation.
stimulation of the ERK (zeige EPHB2 ELISA Kits)/NF-kappaB (zeige NFKB1 ELISA Kits) pathway by Porphyromonas gingivalis led to transactivation of the CD36 promoters, thereby upregulating CD36 expression in the infected macrophages.
Nonclassical monocytes crawl/patrol along the vessel wall during early atherogenesis via CD36 signaling.
In conclusion, we demonstrated in this study for the first time that periodontal CD36 expression was associated with MetS (zeige MARS ELISA Kits)-exacerbated periodontitis. We also demonstrated that CD36 is involved in the enhancement by palmitate of LPS (zeige TLR4 ELISA Kits)-induced inflammatory molecule expression in macrophages.
Results show that CD36 and Platelet-Activating Factor Receptor (zeige PTAFR ELISA Kits) are important mediators of house dust mites (HDM (zeige HDAC3 ELISA Kits)) allergy development and that inhibiting HDM (zeige HDAC3 ELISA Kits) engagement with phosphorylcholine receptors in the lung protects against allergic airway disease.
Our results suggest that LPA-enhanced foam cell formation is mediated by LPA1 (zeige LPAR1 ELISA Kits)/3 -AKT (zeige AKT1 ELISA Kits) activation and subsequent SRBI (zeige SCARB1 ELISA Kits) expression.
These findings suggest that atherogenic conditions critically regulate platelet CD36 signaling by increasing superoxide radical anion and hydrogen peroxide through a mechanism that promotes activation of MAPK (zeige MAPK1 ELISA Kits) ERK5 (zeige MAPK7 ELISA Kits).
the results obtained from Ccr2 (zeige CCR2 ELISA Kits)(-/-), Cd36(-/-), and CD36 bone marrow chimeric mice showed that sequestration in the absence of CD36-mediated phagocytic clearance by monocytes leads to exaggerated lung pathologic features.
In addition, purinergic receptor P2X, ligand-gated ion channel (zeige ZACN ELISA Kits) 7 (P2X7 (zeige P2RX7 ELISA Kits)) was downregulated in CD36-knockdown 3T3-L1 cells, suggesting that the suppression of CD36 attenuates adipogenesis via the P2X7 (zeige P2RX7 ELISA Kits) pathway in 3T3-L1 cells.
Data suggest that the transmembrane domains of Tlr4 (zeige TLR4 ELISA Kits) and Tlr6 (zeige TLR6 ELISA Kits) have essential roles in Tlr4 (zeige TLR4 ELISA Kits)/Tlr6 (zeige TLR6 ELISA Kits)/Cd36 receptor multimerization and activation; disruption of receptor multimerization (here, using a recombinant peptide fragment from Tlr4 (zeige TLR4 ELISA Kits) transmembrane domain) reduces secretion of proinflammatory mediators from microglia and ultimately rescues neurons from death.
The inhibition of Rac1 by NSC23766 inhibited NADPH oxidase activity and ROS generation induced by high glucose concentrations in INS-1 & human 1.1b4 beta cells. Inhibition of Rac1-NOX complex activation by NSC23766 significantly reduced CD36 expression in INS-1 and human 1.1b4 beta cell membrane fractions.
Review of the regulation and post-translational modification of CD36 and its role in renal pathophysiology and chronic kidney disease.
The A allele of the rs1761667 single nucleotide polymorphism in CD36 is associated with decreased fat and sugar intake in obese children and adolescents.
The present study concluded that miR (zeige MLXIP ELISA Kits)-758-5p decreases lipid accumulation of foam cell via regulating CD36-mediated cholesterol uptake.
Data show that all the six inflammation-related CpG-SNPs genotypes including IL1B (zeige IL1B ELISA Kits) rs16944, IL1R2 (zeige IL1R2 ELISA Kits) rs2071008, PLA2G7 (zeige Lp-PLA2 ELISA Kits) rs9395208, FAM5C rs12732361, CD40 (zeige CD40 ELISA Kits) rs1800686, and CD36 rs2065666 were associated with coronary heart disease (CHD (zeige CHDH ELISA Kits)), suggesting an important role of inflammation in the risk of CHD (zeige CHDH ELISA Kits).
CD36 single nucleotide polymorphisms rs1194182 and rs10499859 reduce risk to pulmonary tuberculosis in a Chinese Han population.
CD36 and MARCO are associated with the susceptibility of Chinese Han females to carotid atherosclerosis. Menopausal status may affect the association between gene polymorphisms and carotid atherosclerosis in the female Chinese Han population.
this study shows that diet-induced obesity links to estrogen receptor (zeige ESR1 ELISA Kits)-positive breast cancer progression via LPA (zeige APOA ELISA Kits)/PKD-1 (zeige PKD1 ELISA Kits)-CD36 signaling-mediated microvascular remodeling
High CD36 expression is associated with Acute Monocytic Leukemia (zeige KAT6B ELISA Kits).
These results suggest that increased expression of hepatic CD36 and SREBP-1 (zeige SREBF1 ELISA Kits) is relevant in the obesity-driven lipid accumulation in the liver of dairy cows during late gestation.
Gammadelta T cells express CD36 and it contributes to responses by these cells to microbial lipoteichoic acid.
Niacin Reduces serum level and adipose mRNA expression of leptin (zeige LEP ELISA Kits) and up-regulates PPARgamma (zeige PPARG ELISA Kits) and CD36 mRNA expression in hypercholesterolemic rabbits.
Amyloid-beta inhibits No-cGMP signaling in a CD36- and CD47 (zeige CD47 ELISA Kits)-dependent manner
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
, enkephalin convertase
, prohormone-processing carboxypeptidase
, PAS IV
, fatty acid translocase
, glycoprotein IIIb
, platelet glycoprotein 4
, platelet glycoprotein IV
, CD36 antigen (collagen type I receptor, thrombospondin receptor)
, PAS-4 protein
, cluster determinant 36
, leukocyte differentiation antigen CD36
, scavenger receptor class B, member 3
, CD36 antigen like
, CD36 antigen
, adipocyte membrane protein
, collagen type I receptor thrombospondin receptor
, fatty acid transport protein
, fatty acid translocase/CD36
, collagen type I receptor, thrombospondin receptor
, FAT tumor suppressor homolog 1
, cadherin FAT1 isoform +12
, protocadherin Fat 1
, FAT tumor suppressor homolog 1 (Drosophila)
, HDL QTL 1
, scavenger receptor class B member 1
, scavenger receptor class B type I
, scavenger receptor class B1