anti-Human CBL Antikörper für Enzyme Immunoassay

Recommended CBL Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antikörper
  • 4732447J05Rik
  • Cbl-2
  • c-Cbl
  • cbl
  • C-CBL
  • CBL2
  • FRA11B
  • NSLL
  • RNF55
  • c-cbl-like
  • RGD1561386
  • Casitas B-lineage lymphoma
  • Cbl proto-oncogene
  • Cbl
  • CBL
Epitop
C-Term
43
43
28
28
19
6
5
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Human, Maus, Schwein, Ratte (Rattus)
278
171
161
7
5
4
3
3
2
1
1
1
Wirt
Ziege
222
46
15
1
Klonalität
Polyklonal
Konjugat
Dieser CBL Antikörper ist unkonjugiert
7
7
7
7
6
5
5
5
5
5
5
5
5
5
4
2
2
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
198
76
74
65
62
50
20
17
11
6
5
3
3
2
1
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5552703
$ 411.13
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5554671 EIA IF WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1105707 EIA IF IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 3B12 3

General

Antigen Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antikörper
Epitop C-Term
(43), (43), (28), (28), (19), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Human, Maus, Schwein, Ratte (Rattus)
(278), (171), (161), (7), (5), (4), (3), (3), (2), (1), (1), (1)
Wirt Ziege
(222), (46), (15), (1)
Klonalität
Polyklonal
Konjugat Dieser CBL Antikörper ist unkonjugiert
(7), (7), (7), (7), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(198), (76), (74), (65), (62), (50), (20), (17), (11), (6), (5), (3), (3), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CBL Antikörper

Target Details CBL Anwendungsinformationen Handhabung Bilder
Sequenz C-REFVSISSPA HVAT
Spezifität This antibody detects RNF55 / CBL at C-term.
Kreuzreaktivität (Details) Species reactivity (expected):Human, Rat, Dog, Pig, Cow.
Species reactivity (tested):Mouse.
Reinigung Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Immunogen Peptide from C Terminus of the protein sequence according to NP_005179.2 Genename: CBL

Target Details CBL

Produktdetails anti-CBL Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung CBL / RNF55 (CBL Antibody Abstract)
Hintergrund Cbl (also designated the c-Cbl proto-oncogene, E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene and RING finger protein 55) has been identified as the cellular homolog of the v-Cbl oncogene isolated from an NFS/N mouse that developed a pre-B cell lymphoma following infection with the replication-competent Cas Br-M murine leukemic virus. c-Cbl is expressed at relatively high levels in a wide range of hematopoietic tumor cell lines as well as in normal tissues such as thymus and testis. The c-Cbl gene product has been identified as a cytoplasmic protein with apparent DNA binding and dimerization domains characteristic of transcription factors. A single c-Cbl locus termed CBL2 has been mapped to human chromosome 11q23. This region of chromosome 11 is involved in translocations and deletions in a broad range of leukemias, c-Cbl has been found to be translocated from chromosome 11 in leukemias with either t(4,11) or t(11,14) abnormalities.Synonyms: CBL2, Casitas B-lineage lymphoma proto-oncogene, E3 ubiquitin-protein ligase CBL, Proto-oncogene c-CBL, RING finger protein 55, Signal transduction protein CBL, c-CBL
Gen-ID 867
NCBI Accession NP_005179
UniProt P22681
Pathways T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals

Anwendungsinformationen

Produktdetails anti-CBL Antikörper Target Details CBL Handhabung Bilder zurück nach oben
Applikationshinweise Peptide ELISA: Limit dilution 1: 32000. Western blot: 1-3 μg/mL. Approx 120 kDa band seen in 3T3 lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CBL Antikörper Target Details CBL Anwendungsinformationen Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.