anti-Erythrocyte Ankyrin (ANK1) Antikörper

Bezeichnung:
anti-Ankyrin 1, Erythrocytic Antikörper (ANK1)
Auf www.antikoerper-online.de finden Sie aktuell 66 Ankyrin 1, Erythrocytic (ANK1) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Erythrocyte Ankyrin Kits (2) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 75 Erythrocyte Ankyrin Produkte verfügbar.
Synonyme:
ANK, Ank-1, ANK1, CHANK1, nb, pale, SPH1, SPH2, wu:fa09h06, zgc:101835

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Am meisten referenzierte anti-Erythrocyte Ankyrin Antikörper

  1. Cow (Bovine) Polyclonal Erythrocyte Ankyrin Primary Antibody für IHC, WB - ABIN2775478 : Chang, Ruan: Exploration of pressure-induced dissociation of pyruvate oxidase. in Cellular and molecular biology (Noisy-le-Grand, France) 2004 (PubMed)
    Zeige alle 2 Referenzen für 2775478

  2. Human Monoclonal Erythrocyte Ankyrin Primary Antibody für ICC, IF - ABIN2485538 : Bennett, Baines: Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. in Physiological reviews 2001 (PubMed)

  3. Dog (Canine) Polyclonal Erythrocyte Ankyrin Primary Antibody für WB - ABIN2776925 : Bok, Plazuk, Hryniewicz-Jankowska, Chorzalska, Szmaj, Dubielecka, Stebelska, Diakowski, Lisowski, Langner, Sikorski: Lipid-binding role of betaII-spectrin ankyrin-binding domain. in Cell biology international 2007 (PubMed)

Weitere Antikörper gegen Erythrocyte Ankyrin Interaktionspartner

Human Ankyrin 1, Erythrocytic (ANK1) Interaktionspartner

  1. ANK1 is up-regulated 4-fold in Alzheimer disease microglia, but not in neurons or astrocytes from the same individuals.

  2. Two novel mutations in ANK1 (Y216X and E142X) are responsible for hereditary spherocytosis.

  3. These results suggest that sAnk1 interacts with SLN (zeige SLN Antikörper) both directly and in complex with SERCA1 (zeige ATP2A1 Antikörper) and reduces SLN's inhibitory effect on SERCA1 (zeige ATP2A1 Antikörper) activity.

  4. Mutational characteristics of ANK1 and SPTB (zeige SPTB Antikörper) genes in Korean hereditary spherocytosis have been described.

  5. Ankyrin-1 is induced to a greater extent than the embedded miRNA following DNA damage.

  6. analysis of a novel p.Q1772X ANK1 mutation in a Korean family with hereditary spherocytosis [case report of two family members]

  7. The study reports the refinement for a protein heterodimer complex using limited EPR (zeige EREG Antikörper) spectroscopic data and a rigid-body docking algorithm: a three-dimensional model for an ankyrin 1-BND3 (zeige SLC4A1 Antikörper) complex.

  8. A novel L1340P mutation in the ANK1 gene is associated with hereditary spherocytosis.

  9. Our analyses suggest that these DNA methylation (zeige HELLS Antikörper) changes may have a role in the onset of Alzheimer disease given that we observed them in presymptomatic subjects and that six of the validated genes connect to a known susceptibility gene network.

  10. We identified a differentially methylated region in the ankyrin 1 (ANK1) gene that was associated with neuropathology in the entorhinal cortex, a primary site of Alzheimer disease manifestation.

Mouse (Murine) Ankyrin 1, Erythrocytic (ANK1) Interaktionspartner

  1. With increasing age (at 12-15 mo of age) extensor digitorum longus (EDL (zeige LIPG Antikörper)) skeletal muscles of sAnk1 KO mice develop prematurely large tubular aggregates.

  2. Study shows a direct interaction between beta-III spectrin (zeige SPTBN2 Antikörper) and erythroid ankyrin in the cerebellum and to demonstrate a critical role for beta-III spectrin (zeige SPTBN2 Antikörper) in maintaining ankyrin R throughout the Purkinje cell dendritic tree.

  3. Hema6 mutation of ankyrin-1 causes hereditary spherocytosis in mice through a mild reduction of protein expression.

  4. Suppression of hepcidin (zeige HAMP Antikörper) expression and iron overload mediate Salmonella susceptibility in ankyrin 1-mutated mice.

  5. We conclude that increased malaria resistance due to ankyrin-1 deficiency is caused by the intraerythrocytic death of P. chabaudi parasites.

  6. These results demonstrate that mammalian erythroblast enucleation does not depend on the membrane integrity generated by the ankyrin-band 3 (zeige SLC4A1 Antikörper) complex.

  7. The Ank1(E924X) strain provides a novel tool to study Ank1 and model HS.

  8. A spontaneous mutation, normoblastosis (Ank1nb) in mice provides an important animal model for human ankyrin-deficient anemias.

  9. Results support a role of obscurin (zeige OBSCN Antikörper) in mediating the subcellular localization of small ankyrin1 isoforms in striated (zeige NSDHL Antikörper) muscle cells.

  10. the organization of obscurin (zeige OBSCN Antikörper) at different locations in the sarcomere changes during muscle development and that this might affect the interaction with ank1.5.

Erythrocyte Ankyrin (ANK1) Antigen-Profil

Beschreibung des Gens

Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified.

Alternative names and synonyms associated with Erythrocyte Ankyrin (ANK1)

  • ankyrin 1, erythrocytic (ANK1) Antikörper
  • ankyrin 1, erythrocytic (ank1) Antikörper
  • ankyrin 1, erythrocytic (Ank1) Antikörper
  • ankyrin 1, erythroid (Ank1) Antikörper
  • ANK Antikörper
  • Ank-1 Antikörper
  • ANK1 Antikörper
  • CHANK1 Antikörper
  • nb Antikörper
  • pale Antikörper
  • SPH1 Antikörper
  • SPH2 Antikörper
  • wu:fa09h06 Antikörper
  • zgc:101835 Antikörper

Bezeichner auf Proteinebene für ANK1

ankyrin 1, erythrocytic , erythroid ankyrin , ankyrin-1-like , ANK-1 , ankyrin-1 , ankyrin-R , erythrocyte ankyrin , ankyrin 1, erythroid , normoblastic anemia

GENE ID SPEZIES
396311 Gallus gallus
449796 Danio rerio
613080 Xenopus (Silurana) tropicalis
736634 Pan troglodytes
100036926 Xenopus laevis
100055459 Equus caballus
100388861 Callithrix jacchus
100482591 Ailuropoda melanoleuca
100155697 Sus scrofa
286 Homo sapiens
353108 Bos taurus
306570 Rattus norvegicus
482842 Canis lupus familiaris
11733 Mus musculus
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