Erythrocyte Ankyrin Produkte
(Ankyrin 1, Erythrocytic (ANK1))
Kategorien
Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified. [provided by RefSeq, Dec 2008].
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Ausgewählte Erythrocyte Ankyrin Kategorien
Erythrocyte Ankyrin Antikörper
High quality antibodies with extensive validation data.
Erythrocyte Ankyrin ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene Erythrocyte Ankyrin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IF
Validierungen
- (3)
Kat. Nr.
ABIN2485521
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IF
Validierungen
- (3)
Kat. Nr.
ABIN2485534
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IF
Validierungen
- (3)
Kat. Nr.
ABIN2485533
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Erythrocyte Ankyrin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964879
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1121977
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Erythrocyte Ankyrin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345068
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7416055
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Erythrocyte Ankyrin Produkten
: "ANK1 Methylation regulates expression of MicroRNA-486-5p and discriminates lung tumors by histology and smoking status." in: Cancer letters, Vol. 410, pp. 191-200, (2017) (PubMed).: "The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration." in: Cell death & disease, Vol. 7, pp. e2184, (2016) (PubMed).
: "Upregulated expression of cardiac ankyrin repeat protein in human failing hearts due to arrhythmogenic right ventricular cardiomyopathy." in: European journal of heart failure, Vol. 11, Issue 6, pp. 559-66, (2009) (PubMed).
: "Functional links between membrane transport and the spectrin cytoskeleton." in: The Journal of membrane biology, Vol. 211, Issue 3, pp. 151-61, (2006) (PubMed).
Synonyme und alternative Namen zu Erythrocyte Ankyrin
ankyrin 1 (ANK1), ankyrin 1, erythrocytic a (ank1a), ankyrin 1 (ank1), ankyrin 1 L homeolog (ank1.L), ankyrin 1, erythrocytic (ANK1), ankyrin 1 (Ank1), ankyrin 1, erythroid (Ank1), ank, ANK, Ank-1, ANK1, CHANK1, nb, pale, sph1, SPH1, sph2, SPH2, wu:fa09h06, zgc:101835Bezeichner auf Proteinebene für Erythrocyte Ankyrin
- ankyrin 1, erythrocytic
- erythroid ankyrin
- ankyrin-1-like
- ANK-1
- ankyrin-1
- ankyrin-R
- erythrocyte ankyrin
- ankyrin 1, erythroid
- normoblastic anemia
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