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ERVW-1 Produkte

(Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Kategorien

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010].

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Ausgewählte ERVW-1 Kategorien

ERVW-1 Antikörper

High quality antibodies with extensive validation data.

ERVW-1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ERVW-1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7171179
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN635520
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN3042377
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ERVW-1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1353105
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3095756
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3095754
Menge 0.5 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ERVW-1 Produkten

Ruebner, Langbein, Strissel, Henke, Schmidt, Goecke, Faschingbauer, Schild, Beckmann, Strick: "Regulation of the human endogenous retroviral Syncytin-1 and cell-cell fusion by the nuclear hormone receptors PPAR?/RXR? in placentogenesis." in: Journal of cellular biochemistry, Vol. 113, Issue 7, pp. 2383-96, (2012) (PubMed).

Holder, Tower, Forbes, Mulla, Aplin, Abrahams: "Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1." in: Immunology, Vol. 136, Issue 2, pp. 184-91, (2012) (PubMed).

Fischer, Weber, Kuhn, Fitzgerald, Schulze, Friese, Walzel, Markert, Jeschke: "Is galectin-1 a trigger for trophoblast cell fusion?: the MAP-kinase pathway and syncytium formation in trophoblast tumour cells BeWo." in: Molecular human reproduction, Vol. 17, Issue 12, pp. 747-57, (2011) (PubMed).

Ruebner, Strissel, Langbein, Fahlbusch, Wachter, Faschingbauer, Beckmann, Strick: "Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 11, pp. 1143-56, (2010) (PubMed).

Fischer, Redel, Hofmann, Kuhn, Friese, Walzel, Jeschke: "Stimulation of syncytium formation in vitro in human trophoblast cells by galectin-1." in: Placenta, Vol. 31, Issue 9, pp. 825-32, (2010) (PubMed).

Synonyme und alternative Namen zu ERVW-1

endogenous retrovirus group W member 1, envelope (ERVW-1), ENV, ENVW, ERVWE1, HERV-7q, HERV-W-ENV, HERV7Q, HERVW, HERVWENV

Bezeichner auf Proteinebene für ERVW-1

  • HERV-7q envelope protein
  • HERV-W Env glycoprotein
  • HERV-W envelope protein
  • HERV-W_7q21.2 provirus ancestral Env polyprotein
  • HERV-W{7q21.1} provirus ancestral Env polyprotein
  • HERV-tryptophan envelope protein
  • endogenous retroviral family W, env(C7), member 1
  • endogenous retrovirus group W member 1
  • env-W
  • envelope glycoprotein
  • envelope polyprotein gPr73
  • envelope protein
  • enverin
  • human endogenous retrovirus W envC7-1 envelope protein
  • syncytin A
  • syncytin-1
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