anti-Human MRPS12 Antikörper für Enzyme Immunoassay

Recommended MRPS12 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mitochondrial Ribosomal Protein S12 (MRPS12) Antikörper
  • CG7925
  • Dmel\\CG7925
  • EG:BACH59J11.1
  • MRP-S12
  • MRPS12
  • S12
  • Tko
  • l(1)3Ab
  • l(1)tko
  • mRpS12
  • mt-rps12
  • rps12
  • MGC64304
  • GB10531
  • MPR-S12
  • MT-RPS12
  • RPMS12
  • RPS12
  • RPSM12
  • AI327385
  • Rpms12
  • technical knockout
  • mitochondrial ribosomal protein S12
  • 40S ribosomal protein S12, mitochondrial
  • Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins
  • likely mitochondrial ribosomal protein similar to S. cerevisiae YNR036C and to Reclinomonas americana mitochondrial ribosomal protein S12
  • tko
  • mrps12
  • mRpS12
  • MRPS12
  • mrpS12
  • Mrps12
Epitop
AA 35-67, Middle Region
10
9
9
8
8
4
2
2
1
1
1
1
Reaktivität
Human
44
15
11
1
1
1
1
1
1
Wirt
Kaninchen
43
1
Klonalität
Polyklonal
Konjugat
Dieser MRPS12 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
40
25
19
5
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN953516
$ 390.50
Zzgl. Versandkosten $45.00

General

Antigen Mitochondrial Ribosomal Protein S12 (MRPS12) Antikörper
Epitop AA 35-67, Middle Region
(10), (9), (9), (8), (8), (4), (2), (2), (1), (1), (1), (1)
Reaktivität Human
(44), (15), (11), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(43), (1)
Klonalität
Polyklonal
Konjugat Dieser MRPS12 Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(40), (25), (19), (5)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MRPS12 Antikörper

Target Details MRPS12 Anwendungsinformationen Handhabung Referenzen für anti-MRPS12 Antikörper (ABIN953516) Bilder
Spezifität This antibody recognizes Human MRPS12 (Center).
Reinigung Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 35-67 amino acids from the Central region of Human MRPS12 Genename: MRPS12
Isotyp Ig

Target Details MRPS12

Produktdetails anti-MRPS12 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-MRPS12 Antikörper (ABIN953516) Bilder zurück nach oben
Antigen
Andere Bezeichnung MRPS12 (MRPS12 Antibody Abstract)
Hintergrund Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same proteinSynonyms: 28S ribosomal protein S12, MRP-S12, MT-RPS12, RPMS12, RPSM12, S12mt, mitochondrial
Gen-ID 6183
NCBI Accession NP_066930
Pathways Sensory Perception of Sound

Anwendungsinformationen

Produktdetails anti-MRPS12 Antikörper Target Details MRPS12 Handhabung Referenzen für anti-MRPS12 Antikörper (ABIN953516) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MRPS12 Antikörper Target Details MRPS12 Anwendungsinformationen Referenzen für anti-MRPS12 Antikörper (ABIN953516) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-MRPS12 Antikörper (ABIN953516)

Produktdetails anti-MRPS12 Antikörper Target Details MRPS12 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Zanotto, Häkkinen, Teku, Shen, Ribeiro, Jacobs: "NF-Y influences directionality of transcription from the bidirectional Mrps12/Sarsm promoter in both mouse and human cells." in: Biochimica et biophysica acta, Vol. 1789, Issue 5, pp. 432-42, 2009

Russo, Cirulli, Amoresano, Pucci, Pietropaolo, Russo: "cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins." in: Biochimica et biophysica acta, Vol. 1779, Issue 12, pp. 820-9, 2008

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005

Cui, Wang, Zhang, Bi, Guo, Lu: "Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene." in: World journal of gastroenterology : WJG, Vol. 9, Issue 9, pp. 1892-6, 2003

Zhang, Gerstein: "Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome." in: Genomics, Vol. 81, Issue 5, pp. 468-80, 2003

Bilder

Produktdetails anti-MRPS12 Antikörper Target Details MRPS12 Anwendungsinformationen Handhabung Referenzen für anti-MRPS12 Antikörper (ABIN953516) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (AA 35-67), (Middle Region) antibody (ABIN953516) Formalin fixed and paraffin embedded human pancreas tissue stained with MRPS12 follow...
Western Blotting (WB) image for anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (AA 35-67), (Middle Region) antibody (ABIN953516) Western blot analysis of MRPS12 in CEM cell line lysates (35ug/lane). This demonstrat...