anti-Zebrafisch GABRB3 Antikörper für Western Blotting

Recommended GABRB3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) Antikörper
  • GABRB3
  • eca5
  • LOC100230475
  • ECA5
  • A230092K12Rik
  • AW049585
  • Cp1
  • Gabrb-3
  • beta3
  • gamma-aminobutyric acid (GABA) A receptor, beta 3
  • gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
  • GABRB3
  • gabrb3
  • LOC100230475
  • Gabrb3
Epitop
Middle Region
41
14
11
9
4
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
102
93
85
11
11
6
5
5
4
2
2
2
2
2
1
1
1
Wirt
Kaninchen
61
43
21
1
Klonalität
Polyklonal
Konjugat
Dieser GABRB3 Antikörper ist unkonjugiert
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
100
57
56
55
44
21
18
17
13
3
3
2
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2776245
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN958986 IHC (p) WB Rabbit AA 180-229 Anmelden zum Anzeigen Polyclonal
1 ABIN1582171 ELISA WB Rabbit pSer408, pSer409 Anmelden zum Anzeigen Polyclonal

General

Antigen gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) Antikörper
Epitop Middle Region
(41), (14), (11), (9), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
(102), (93), (85), (11), (11), (6), (5), (5), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(61), (43), (21), (1)
Klonalität
Polyklonal
Konjugat Dieser GABRB3 Antikörper ist unkonjugiert
(6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(100), (57), (56), (55), (44), (21), (18), (17), (13), (3), (3), (2), (2), (2), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GABRB3 Antikörper

Target Details GABRB3 Anwendungsinformationen Handhabung Referenzen für anti-GABRB3 Antikörper (ABIN2776245) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977216.
Sequenz ESYGYTTDDI EFYWRGGDKA VTGVERIELP QFSIVEHRLV SRNVVFATGA
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against GABRB3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human GABRB3

Target Details GABRB3

Produktdetails anti-GABRB3 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-GABRB3 Antikörper (ABIN2776245) Bilder zurück nach oben
Antigen
Andere Bezeichnung GABRB3 (GABRB3 Antibody Abstract)
Hintergrund GABRB3 is a member of the ligand-gated ionic channel family. GABRB3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described.
Alias Symbols: MGC9051, ECA5
Protein Interaction Partner: MEOX2, UBC, UBQLN1, ARFGEF2, PPP2CA, AKAP5, GNB2L1, PRKCA, PRKACA,
Protein Size: 473
Molekulargewicht 52 kDa
Gen-ID 2562
NCBI Accession NM_021912, NP_068712
UniProt P28472
Pathways Sensory Perception of Sound

Anwendungsinformationen

Produktdetails anti-GABRB3 Antikörper Target Details GABRB3 Handhabung Referenzen für anti-GABRB3 Antikörper (ABIN2776245) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 473 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GABRB3 Antikörper Target Details GABRB3 Anwendungsinformationen Referenzen für anti-GABRB3 Antikörper (ABIN2776245) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GABRB3 Antikörper (ABIN2776245)

Produktdetails anti-GABRB3 Antikörper Target Details GABRB3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Tanaka, Olsen, Medina, Schwartz, Alonso, Duron, Castro-Ortega, Martinez-Juarez, Pascual-Castroviejo, Machado-Salas, Silva, Bailey, Bai, Ochoa, Jara-Prado, Pineda, Macdonald, Delgado-Escueta: "Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy." in: American journal of human genetics, Vol. 82, Issue 6, pp. 1249-61, 2008

Bilder

Produktdetails anti-GABRB3 Antikörper Target Details GABRB3 Anwendungsinformationen Handhabung Referenzen für anti-GABRB3 Antikörper (ABIN2776245) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (Middle Region) antibody (ABIN2776245) Immunohistochemistry with Lung tissue at an antibody concentration of 5µg/ml using an...