anti-Huhn GABRB3 Antikörper für Western Blotting

Recommended GABRB3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) Antikörper
  • GABRB3
  • eca5
  • LOC100230475
  • ECA5
  • A230092K12Rik
  • AW049585
  • Cp1
  • Gabrb-3
  • beta3
  • gamma-aminobutyric acid (GABA) A receptor, beta 3
  • gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
  • GABRB3
  • gabrb3
  • LOC100230475
  • Gabrb3
Epitop
pSer408, pSer409
41
14
11
9
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Huhn, Rind (Kuh), Hund, Human, Maus, Non-Human Primate, Ratte (Rattus), Xenopus laevis, Zebrafisch (Danio rerio)
102
93
85
11
11
7
6
6
4
3
2
2
1
1
1
Wirt
Kaninchen
61
43
21
1
Klonalität
Polyklonal
Konjugat
Dieser GABRB3 Antikörper ist unkonjugiert
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
100
57
57
55
44
21
18
17
13
3
3
2
2
2
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
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Produktnummer ABIN5555560
$ 375.38
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1582171 ELISA WB Rabbit pSer408, pSer409 Anmelden zum Anzeigen Polyclonal

General

Antigen gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) Antikörper
Epitop pSer408, pSer409
(41), (14), (11), (9), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Huhn, Rind (Kuh), Hund, Human, Maus, Non-Human Primate, Ratte (Rattus), Xenopus laevis, Zebrafisch (Danio rerio)
(102), (93), (85), (11), (11), (7), (6), (6), (4), (3), (2), (2), (1), (1), (1)
Wirt Kaninchen
(61), (43), (21), (1)
Klonalität
Polyklonal
Konjugat Dieser GABRB3 Antikörper ist unkonjugiert
(6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(100), (57), (57), (55), (44), (21), (18), (17), (13), (3), (3), (2), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GABRB3 Antikörper

Target Details GABRB3 Anwendungsinformationen Handhabung Bilder
Spezifität The antibody has been directly tested for reactivity in Western blots with rat tissue. Specific for the ~53k GABAA receptor beta-3 subunit phosphorylated at Ser408/409. Immunolabeling of the GABAA band is completely blocked by the phospho-peptide used as antigen but not by the corresponding dephospho-peptide.
Kreuzreaktivität (Details) Species reactivity (expected):Bovine, Canine, Chicken, Human, Mouse, non-Human primates, Xenopus and Zebrafish.
Species reactivity (tested):Rat.
Reinigung Affinity Chromatography.
Immunogen Phosphopeptide corresponding to amino acid residues surrounding the di-phospho- Ser408/409 of the Rat GABAA receptor, beta-3 subunit.
Isotyp IgG

Target Details GABRB3

Produktdetails anti-GABRB3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung GABRB3 (GABRB3 Antibody Abstract)
Hintergrund Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six Alpha's, four Beta's and four Gamma's, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990, Whiting et al., 1999, Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for Alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a Gamma-subunit is required for benzodiazepine modulation. Phosphorylation of Serine 408 and Serine 409 within the Beta-3 subunit have been shown to be critical for the functional modulation of Beta-3 containing recombinant receptors (Brandon et al., 2000).Synonyms: GABA A receptor subunit beta-3, GABRB-3, Gamma-aminobutyric acid receptor subunit beta-3
Gen-ID 24922
NCBI Accession NP_058761
Pathways Sensory Perception of Sound

Anwendungsinformationen

Produktdetails anti-GABRB3 Antikörper Target Details GABRB3 Handhabung Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GABRB3 Antikörper Target Details GABRB3 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handhabung Avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store the antibody undiluted (in aliquots) at -20 °C.