anti-RHEB (RHEB) Antikörper

anti-Ras Homolog Enriched in Brain Antikörper (RHEB)
Auf finden Sie aktuell 135 Ras Homolog Enriched in Brain (RHEB) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RHEB Proteine (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 161 RHEB Produkte verfügbar.
im:7161941, RHEB, RHEB2, zgc:153231

Meistgesuchte Reaktivitäten zu anti-RHEB (RHEB) Antikörper

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anti-Human RHEB Antikörper:

anti-Mouse (Murine) RHEB Antikörper:

anti-Rat (Rattus) RHEB Antikörper:

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Am meisten referenzierte anti-RHEB Antikörper

  1. Human Polyclonal RHEB Primary Antibody für EIA, IHC (p) - ABIN954537 : Zheng, Liu, Liu, Li, Yu, Luo: Ras homologue enriched in brain is a critical target of farnesyltransferase inhibitors in non-small cell lung cancer cells. in Cancer letters 2010 (PubMed)
    Zeige alle 3 Referenzen für 954537

  2. Human Polyclonal RHEB Primary Antibody für WB - ABIN2476356 : Kageyama, Takahashi: Pepsinogens and pepsins from gastric mucosa of Japanese Monkey. Purification and characterization. in Journal of biochemistry 1976 (PubMed)
    Zeige alle 2 Referenzen für 2476356

  3. Human Monoclonal RHEB Primary Antibody für ELISA, WB - ABIN519784 : Menon, Dibble, Talbott, Hoxhaj, Valvezan, Takahashi, Cantley, Manning: Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome. in Cell 2014 (PubMed)

  4. Cow (Bovine) Polyclonal RHEB Primary Antibody für IHC, WB - ABIN2786819 : Eom, Han, Yi, Shin, Cui, Park: RHEB expression in fibroadenomas of the breast. in Pathology international 2008 (PubMed)

Weitere Antikörper gegen RHEB Interaktionspartner

Human Ras Homolog Enriched in Brain (RHEB) Interaktionspartner

  1. By interfering with TSC (zeige SLC12A3 Antikörper)-Rheb complex, arginine relieves allosteric inhibition of Rheb by TSC (zeige SLC12A3 Antikörper). Arginine cooperates with growth factor signaling which further promotes dissociation of TSC2 (zeige TSC2 Antikörper) from lysosomes and activation of mTORC1.

  2. Data show that Rheb/p27 (zeige PAK2 Antikörper) axis induces autophagy-dependent cancer cell survival under stress conditions.

  3. Mutations in the TSC2 (zeige TSC2 Antikörper)-RHEB-mTOR (zeige FRAP1 Antikörper) signaling axis may lead to a loss of inhibitory inputs thus conferring a survival advantage to a dividing tumor cell.

  4. Activation of CNTF (zeige CNTF Antikörper)/CNTFRalpha (zeige CNTFR Antikörper) signaling pathway by hRheb(S16H) transduction of dopaminergic neurons

  5. RGS10 (zeige RGS10 Antikörper) could serve in a novel, and previously unknown, role by accelerating the hydrolysis of GTP (zeige AK3 Antikörper) from Rheb in ovarian cancer cells.

  6. In TSC2 (zeige TSC2 Antikörper)-deficient angiomyolipoma patient cells, IRF7 (zeige IRF7 Antikörper) is a pivotal factor in the Rheb/mTOR (zeige FRAP1 Antikörper) pathway.

  7. These results establish CAD (zeige CAD Antikörper) as a downstream effector of Rheb and suggest a possible role of Rheb in regulating de novo pyrimidine nucleotide synthesis.(Rheb small GTPases, which consist of Rheb1 and Rheb2 (also known as RhebL1 (zeige RHEBL1 Antikörper))

  8. In vitro data indicated that miR (zeige MLXIP Antikörper)-155 suppressed the macrophage-mediated bacterial phagocytosis and intracellular killing of Pseudomonas aeruginosa by targeting Rheb (Ras homolog enriched in brain).

  9. Data indicate that Rheb G63A stimulated phosphorylation of the mTORC1 substrate p70S6 kinase more strongly than wild-type, thus offering a new tool for mammalian target of rapamycin (mTOR (zeige FRAP1 Antikörper)) signaling.

  10. study defines Rheb as a novel physiological regulator of BACE1 (zeige BACE Antikörper) levels and Abeta (zeige APP Antikörper) generation, and the Rheb-BACE1 (zeige BACE Antikörper) circuitry may have a role in brain biology and disease.

Mouse (Murine) Ras Homolog Enriched in Brain (RHEB) Interaktionspartner

  1. Rheb is an important negative regulator of beige (zeige LYST Antikörper) fat development and thermogenesis. Rheb is able to suppress the beiging effect through an mTORC1-independent mechanism, via PDE4D5-dependent downregulation of the cAMP-PKA signaling pathway.

  2. Rheb and TSC2 (zeige TSC2 Antikörper) have roles in the mechanical activation of mTOR (zeige FRAP1 Antikörper) signaling

  3. EAAT4 (zeige SLC1A6 Antikörper) was downregulated due to the loss of Rheb1 in Purkinje cells; mTORC1 was downregulated and Akt (zeige AKT1 Antikörper) was upregulated in Rheb1 cKO mice, suggesting that mTORC1 and Akt (zeige AKT1 Antikörper) may be related to the downregulation of EAAT4 (zeige SLC1A6 Antikörper); Rheb1 knockout decreased EAAT4 (zeige SLC1A6 Antikörper) currents and slowed down the kinetics of AMPA (zeige GRIA3 Antikörper) currents; Rheb1 deficiency did not affect the morphology of Purkinje cell layer and the development of Purkinje cells

  4. Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway.

  5. Rheb activation disrupts neuronal spine synapse formation via syntenin (zeige SDCBP Antikörper) accumulation in tuberous sclerosis complex.

  6. We conclude that in contrast to TORC1 (zeige CRTC1 Antikörper) hyper-activity, cognitive function is not very sensitive to sustained and specific down-regulation of TORC1 (zeige CRTC1 Antikörper) activity.

  7. Rheb protein was mainly detected in apoptotic retinal ganglion cells following light injury.

  8. PDK4 (zeige PDK4 Antikörper) promotes tumorigenesis through activation of the CREB (zeige CREB1 Antikörper)-RHEB-mTORC1 signaling cascade.

  9. The small GTPase (zeige RACGAP1 Antikörper) Rheb is required for spermatogenesis but not oogenesis.

  10. The paper proposed a novel pathway/mechanism involving Rheb/mTORC1/S6K (zeige RPS6KB1 Antikörper) signaling to explain how C2-ceramide impairs insulin (zeige INS Antikörper) signaling via Akt (zeige AKT1 Antikörper) phosphorylation.

RHEB Antigen-Profil

Beschreibung des Gens

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Alternative names and synonyms associated with RHEB

  • Ras homolog enriched in brain (RHEB) Antikörper
  • Ras homolog enriched in brain (rheb) Antikörper
  • ras homolog enriched in brain (rheb) Antikörper
  • Ras homolog enriched in brain (Rheb) Antikörper
  • im:7161941 Antikörper
  • RHEB Antikörper
  • RHEB2 Antikörper
  • zgc:153231 Antikörper

Bezeichner auf Proteinebene für RHEB

Ras homolog enriched in brain , RAS-homolog enriched in brain , ras homolog enriched in brain , GTP-binding protein rheb , GTP-binding protein Rheb , Ras homolog enriched in brain 2

475545 Canis lupus familiaris
548676 Xenopus (Silurana) tropicalis
767781 Danio rerio
100528708 Ictalurus punctatus
6009 Homo sapiens
19744 Mus musculus
26954 Rattus norvegicus
420434 Gallus gallus
528204 Bos taurus
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