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Human MME ELISA Kit für Sandwich ELISA - ABIN417259
Goliasch, Pavo, Zotter-Tufaro, Kammerlander, Duca, Mascherbauer, Bonderman: Soluble neprilysin does not correlate with outcome in heart failure with preserved ejection fraction. in European journal of heart failure 2016
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Rat (Rattus) MME ELISA Kit für Sandwich ELISA - ABIN432345
Nagai, Ito, Tanino: Effect of high glucose levels on amyloid β production in retinas of spontaneous diabetes mellitus Otsuka Long-Evans Tokushima fatty rats. in Biological & pharmaceutical bulletin 2015
Human MME ELISA Kit für Sandwich ELISA - ABIN457043
Qian, Ding, Cheng, Zhu, Zhao, Jin, Guan, Zhang, Chen, Xu: Early biomarkers for post-stroke cognitive impairment. in Journal of neurology 2012
Neutral endopeptidase 24.11 and DPP-IV (zeige DPP4 ELISA Kits) is superior to DPP-IV (zeige DPP4 ELISA Kits) inhibition alone in preserving intact GLP-1 (zeige GCG ELISA Kits), which implies possibility that the combination has therapeutic potential.
This study provides evidence that NEP 24.11 is an important mediator of the degradation of both endogenous and exogenous glucagon (zeige GCG ELISA Kits) in vivo.
we further analyzed the CpG methylation levels at the DDR1 promoter in EOC cells and found that the CpG methylation levels of DDR1 promoter correlated negatively with the expression of DDR1 along the EMT spectrum. Therefore, EMT stratification could be a potential biomarker to predict patient response to DDR1-targeting drugs.
This study suggested that DDR1 and DDR2 (zeige DDR2 ELISA Kits) knockdown alters brain immunity and significantly reduces the level of triggering receptor expressed on myeloid cells (TREM)-2 (zeige TREM2 ELISA Kits) and microglia.
Isoform b of DDR1 is responsible for collagen I-induced up-regulation of N-cadherin (zeige CDH2 ELISA Kits) and tyrosine 513 of DDR1b is necessary.
CD10 is a necessary component conferring the L1 effects in CRC (zeige CALR ELISA Kits) cells. The identification of gene expression patterns of L1-domain-specific point mutations may provide novel markers and targets for interfering with L1-mediated CRC (zeige CALR ELISA Kits) progression.
High CD10 expression is associated with lymphoma in Waldeyer ring.
Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies
Reduced DDR1 expression may be implicated in impaired melanocyte adhesion process involved in vitiligo (zeige MITF ELISA Kits) pathogenesis
CD10 down expression in follicular lymphoma correlates with gastrointestinal lesion involving the stomach and large intestine
data demonstrate that TGF-beta1 favors linear invadosome formation through the expressions of both the inducers, such as collagen and LOXL2, and the components such as DDR1 and MT1-MMP of linear invadosomes in cancer cells. Meanwhile, our data uncover a new TGF-beta1-dependent regulation of DDR1 expression.
DDR1 overexpression promoted GC cell proliferation (p < 0.05), migration (p < 0.01), and invasion (p < 0.01), and accelerated the growth (p < 0.05) as well as the microvessel formation (p < 0.01) of transplantation tumor in nude mice.
findings define a novel physiological function of Shp2 (zeige PTPN11 ELISA Kits) in TGF-beta1 (zeige TGFB1 ELISA Kits)/MMP12 (zeige MMP12 ELISA Kits)-dependent emphysema, adding insights into potential etiologies for this chronic lung disorder.
Mmp12 (zeige MMP12 ELISA Kits) is expressed early following corneal epithelial injury with highest expression levels at 8 h after injury and lower expression levels at 4 and 8 days after injury. We investigated whether MMP12 (zeige MMP12 ELISA Kits) has an effect on the rate of epithelial repair and cell migration using in vivo and in vitro scratch assays performed on WT and Mmp12 (zeige MMP12 ELISA Kits)(-/-) mice
Rare Variants in MME, Encoding Metalloprotease (zeige ADAMTS7 ELISA Kits) Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies
MMP-12 (zeige MMP12 ELISA Kits) produced by macrophages infiltrating into glomeruli contributed to the degradation of collagen type IV (zeige COL4 ELISA Kits) and fibronectin (zeige FN1 ELISA Kits).
MMP12 (zeige MMP12 ELISA Kits) causes arterial stiffening in mice and suggest that it functions similarly in humans.
These results suggest that MMP-12 (zeige MMP12 ELISA Kits) production during emphysema exacerbation results in increased mortality and disease progression.
study found significant increases of MMP-3 (zeige MMP3 ELISA Kits) and MMP-12 (zeige MMP12 ELISA Kits) mRNA levels and MMP12 (zeige MMP12 ELISA Kits) zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection
The results suggest that pulmonary C fiber involvement in long-term airway inflammation and airway hyperresponsiveness occurred at least partially via modulating MMP-12 (zeige MMP12 ELISA Kits), and the activation of PAR2 (zeige F2RL1 ELISA Kits) might be related to MMP-12 (zeige MMP12 ELISA Kits) production.
MMP-12 (zeige MMP12 ELISA Kits) up-regulation mediated by SARM-TRIF (zeige RNF138 ELISA Kits) signaling pathway contributes to IFN-gamma (zeige IFNG ELISA Kits)-independent airway inflammation and AHR (zeige AHR ELISA Kits) post RSV infection in nude mice.
MMP-12 (zeige MMP12 ELISA Kits) and MMP-13 (zeige MMP13 ELISA Kits) alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.
, neutral endopeptidase
, membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)
, membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
, neprilysin-410 short isoform
, CD167 antigen-like family member A
, PTK3A protein tyrosine kinase 3A
, cell adhesion kinase
, epithelial discoidin domain-containing receptor 1
, mammary carcinoma kinase 10
, neuroepithelial tyrosine kinase
, neurotrophic tyrosine kinase, receptor, type 4
, protein-tyrosine kinase RTK-6
, tyrosine kinase DDR
, tyrosine-protein kinase CAK
, macrophage elastase
, macrophage metalloelastase
, matrix metalloproteinase 12
, matrix metalloproteinase-12
, common acute lymphoblastic leukemia antigen
, neutral endopeptidase 24.11
, skin fibroblast elastase
, common acute lymphocytic leukemia antigen
, membrane metallo-endopeptidase variant 1
, membrane metallo-endopeptidase variant 2
, membrane metallo endopeptidase
, membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase)