MME Produkte
(Membrane Metallo-Endopeptidase (MME))
Kategorien
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq, Jul 2008].
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Ausgewählte MME Kategorien
MME Antikörper
High quality antibodies with extensive validation data.
MME ELISA Kits
Reliable ELISA kits for a wide range of species.
MME Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MME Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN1724914
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN6143900
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7434053
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MME ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN6730947
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957745
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957744
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MME Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275263
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275264
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275262
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MME Produkten
: "Increased granulocyte membrane neprilysin (CD10) expression is associated with better prognosis in heart failure." in: European journal of heart failure, Vol. 21, Issue 4, pp. 537-539, (2020) (PubMed).: "Soluble neprilysin, NT-proBNP, and growth differentiation factor-15 as biomarkers for heart failure in dialysis patients (SONGBIRD)." in: Clinical research in cardiology : official journal of the German Cardiac Society, Vol. 109, Issue 8, pp. 1035-1047, (2020) (PubMed).
: "Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression." in: Phytotherapy research : PTR, Vol. 33, Issue 4, pp. 1114-1121, (2019) (PubMed).
: "Cinacalcet attenuated bone loss via inhibiting parathyroid hormone-induced endothelial-to-adipocyte transition in chronic kidney disease rats." in: Annals of translational medicine, Vol. 7, Issue 14, pp. 312, (2019) (PubMed).
: "Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation." in: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).
: "Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme-like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report." in: Experimental and therapeutic medicine, Vol. 16, Issue 3, pp. 2060-2065, (2018) (PubMed).
: "Improved glycaemia in high-fat-fed neprilysin-deficient mice is associated with reduced DPP-4 activity and increased active GLP-1 levels." in: Diabetologia, Vol. 60, Issue 4, pp. 701-708, (2017) (PubMed).
: "Soluble neprilysin does not correlate with outcome in heart failure with preserved ejection fraction." in: European journal of heart failure, Vol. 18, Issue 1, pp. 89-93, (2016) (PubMed).
: "A Test in Context: Neprilysin: Function, Inhibition, and Biomarker." in: Journal of the American College of Cardiology, Vol. 68, Issue 6, pp. 639-53, (2016) (PubMed).
: "A metanephric adenoma of the kidney associated with polycythemia: A case report." in: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).
Synonyme und alternative Namen zu MME
membrane metalloendopeptidase (MME), membrane metallo endopeptidase (Mme), membrane metallo-endopeptidase (Mme), membrane metalloendopeptidase (Mme), 6030454K05Rik, C85356, CALLA, CD10, NEP, Nep, neprilysin, SFEBezeichner auf Proteinebene für MME
- atriopeptidase
- common acute lymphocytic leukemia antigen
- enkephalinase
- membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)
- membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
- membrane metallo-endopeptidase variant 1
- membrane metallo-endopeptidase variant 2
- neprilysin
- neutral endopeptidase 24.11
- skin fibroblast elastase
- common acute lymphoblastic leukemia antigen
- neutral endopeptidase
- neprilysin-410 short isoform
- membrane metallo endopeptidase
- NEP
- membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase)
- LOW QUALITY PROTEIN: neprilysin
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