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Full name:
V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) ELISA Kits (ERBB3)
Auf www.antikoerper-online.de finden Sie aktuell 29 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) ELISA Kits von 13 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ERBB3 Antikörper (508) und ERBB3 Proteine (41) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 608 ERBB3 Produkte verfügbar.
Synonyme:
c-erbB-3, c-erbB3, C76256, Erbb-3, ERBB3, erbB3-S, Erbb3r, Her3, LCCS2, MDA-BF-1, nuc-ErbB3, p45-sErbB3, p85-sErbB3, p180-ErbB3

Weitere ELISA Kits für ERBB3 Interaktionspartner

Rhesus Monkey V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. Widespread expression of ErbB3 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization.

Pig (Porcine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. data confirmed that an ErbB3-driven pathway mediates a net positive influence in an in vivo model closely resembling human repair

Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. High HER3 expression in colon cancer was associated to distal colon location and low-grade tumor.

  2. Correlate ERBB3 gene SNPs with rheumatoid arthritis susceptibility.

  3. Nrdp1S is a tumour suppressor that which potentiates the Nrdp1 (zeige RNF41 ELISA Kits)-mediated ubiquitination and degradation of ErbB3. An Nrdp1S deficiency may also be an important factor in the loss of Nrdp1 (zeige RNF41 ELISA Kits).

  4. In response to trastuzumab, both HER3 and the metalloprotease (zeige ADAM8 ELISA Kits) ADAM10 (zeige ADAM10 ELISA Kits) are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 ligand heregulin (zeige NRG1 ELISA Kits) from the cell surface to activate HER3 and confer resistance to trastuzumab by inducing compensatory growth factor receptor (zeige RYK ELISA Kits) signaling.

  5. the identification of HER3-V855A and its functional properties for the first time clearly implicates genomic HER3 activation in the pathogenesis of lung cancer.

  6. We report that targeting HER3 and b1 integrin provides a particularly effective combination therapy approach for HER2 (zeige ERBB2 ELISA Kits)-amplified cancers, surpassing the combination of HER2 (zeige ERBB2 ELISA Kits) and b1 integrin targeting, and evading some of the safety concerns associated with direct HER2 (zeige ERBB2 ELISA Kits)-targeting.

  7. These data indicate that erbB3 signaling is critical for both trastuzumab and lapatinib resistances mainly through the PI-3K/Akt (zeige AKT1 ELISA Kits) pathway, whereas IGF-1R (zeige IGF1R ELISA Kits)-initiated Src (zeige SRC ELISA Kits) activation results in trastuzumab resistance without affecting lapatinib sensitivity.

  8. Data show that heat shock protein 90 (HSP90 (zeige HSP90 ELISA Kits)) inhibitor 17-DMAG caused loss of ret proto-oncogene (zeige RET ELISA Kits) protein (RET (zeige RET ELISA Kits)) and proto-oncogene (zeige RAB1A ELISA Kits) protein erbB-3 (ERBB3) phosphorylation and lead to rapid cell death.

  9. Data indicate the role of proto-oncogene (zeige RAB1A ELISA Kits) protein erbB-3 (ErbB3) in hepatitis B virus X protein (HBx)-mediated cell survival.

  10. NRF2 (zeige GABPA ELISA Kits) regulates both HER2 (zeige ERBB2 ELISA Kits) and HER3 receptors to influence cellular responses to HER2 (zeige ERBB2 ELISA Kits) targeting.

Mouse (Murine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Interaktionspartner

  1. Data indicate that Sonic hedgehog (Shh (zeige SHH ELISA Kits)) stimulate branching morphogenesis (BrM (zeige SMARCA2 ELISA Kits)) and induced synthesis of mRNAs for Ptch1 (zeige PTCH1 ELISA Kits) protein, epidermal growth factor (EGF (zeige EGF ELISA Kits)) and receptors of the ErbB (zeige EGFR ELISA Kits) receptors ErbB1 (zeige EGFR ELISA Kits), ErbB2 (zeige ERBB2 ELISA Kits) and ErbB3.

  2. ERBB3 is required for wound healing and for the progression of skin tumors in mice.

  3. The expression of ERBB3 in combination with ERBB4 (zeige ERBB4 ELISA Kits) significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  4. Data indicate that increased expression of erbB3 plays a pivotal role in activating downstream PI-3K/Akt (zeige AKT1 ELISA Kits) pathway and promoting erbB2 (zeige ERBB2 ELISA Kits)-driven mammary/breast tumorigenesis.

  5. Suggest that ERBB3 may promote hepatocellular carcinoma through STAT3 (zeige STAT3 ELISA Kits) activation.

  6. ERBB3 is crucial for the proliferation of Bergmann glia in the developing cerebellum.

  7. ErbB3 plays a key role in migration, as well as in myelination, in mouse Schwann lineage cells.

  8. Knock-down of Erbb3 with siRNA during early differentiation inhibits cardiomyogenesis in embryonic stem cells.

  9. Myocilin (zeige MYOC ELISA Kits) binds to ErbB2 (zeige ERBB2 ELISA Kits)/ErbB3, activates these receptors, and affects the downstream PI3K-AKT (zeige AKT1 ELISA Kits) signaling pathway

  10. PIK3CA (zeige PIK3CA ELISA Kits)(H1047R)-driven tumor growth and PI3K signaling can occur independently of ErbB3 receptor tyrosine kinases.

ERBB3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) Elisa Kit
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3) Elisa Kit
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (Erbb3) Elisa Kit
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3) Elisa Kit
  • c-erbB-3 Elisa Kit
  • c-erbB3 Elisa Kit
  • C76256 Elisa Kit
  • Erbb-3 Elisa Kit
  • ERBB3 Elisa Kit
  • erbB3-S Elisa Kit
  • Erbb3r Elisa Kit
  • Her3 Elisa Kit
  • LCCS2 Elisa Kit
  • MDA-BF-1 Elisa Kit
  • nuc-ErbB3 Elisa Kit
  • p45-sErbB3 Elisa Kit
  • p85-sErbB3 Elisa Kit
  • p180-ErbB3 Elisa Kit

Bezeichner auf Proteinebene für ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , avian erythroblastosis oncogene B 3 , c-erbB-3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , avian erythroblastosis oncogene B 3 receptor , glial growth factor receptor , receptor tyrosine kinase

GENE ID SPEZIES
481105 Canis lupus familiaris
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
100468735 Ailuropoda melanoleuca
2065 Homo sapiens
29496 Rattus norvegicus
13867 Mus musculus
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