anti-EIF2S1 (EIF2S1) Antikörper

Bezeichnung:
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 Antikörper (EIF2S1)
Auf www.antikoerper-online.de finden Sie aktuell 134 Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen EIF2S1 Proteine (19) und EIF2S1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 162 EIF2S1 Produkte verfügbar.
Synonyme:
35kDa, 0910001O23Rik, 2410026C18Rik, CG9946, deIF2alpha, Dmel\\CG9946, EIF-2, eIF-2 a, eIF-2 alpha, EIF-2A, EIF-2alpha, EIF2, eIF2 alpha, eIF2-alpha, EIF2A, eIF2alpha, eif2s1, elF2alpha, fb19d01, IF2A_DROME, l(1)14Cf, l(1)19-153, M(1)8e3-10, M(1)14C, M(1)19-153, wu:fb19d01

Meistgesuchte Reaktivitäten zu anti-EIF2S1 (EIF2S1) Antikörper

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anti-Mouse (Murine) EIF2S1 Antikörper:

anti-Rat (Rattus) EIF2S1 Antikörper:

anti-Human EIF2S1 Antikörper:

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Am meisten referenzierte anti-EIF2S1 Antikörper

  1. Human Monoclonal EIF2S1 Primary Antibody für IF, WB - ABIN393738 : Kulkarni, Mittal, Devasagayam, Pal: Hsp90 mediates activation of the heme regulated eIF-2 alpha kinase during oxidative stress. in Indian journal of biochemistry & biophysics 2010 (PubMed)
    Zeige alle 5 Referenzen für 393738

  2. Mouse (Murine) Polyclonal EIF2S1 Primary Antibody für IF, IHC (p) - ABIN657392 : Shiota, Eto, Yokomizo, Tada, Takeuchi, Masubuchi, Inokuchi, Tatsugami, Kuroiwa, Uchiumi, Seki, Naito: Sorafenib with doxorubicin augments cytotoxicity to renal cell cancer through PERK inhibition. in International journal of oncology 2010 (PubMed)
    Zeige alle 4 Referenzen für 657392

  3. Human Monoclonal EIF2S1 Primary Antibody für EIA, IHC (p) - ABIN781543 : Peña, Harris: Dengue virus modulates the unfolded protein response in a time-dependent manner. in The Journal of biological chemistry 2011 (PubMed)
    Zeige alle 3 Referenzen für 781543

  4. Human Polyclonal EIF2S1 Primary Antibody für IF, IHC (p) - ABIN197542 : Saelens, Kalai, Vandenabeele: Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 2 Referenzen für 197542

  5. Human Polyclonal EIF2S1 Primary Antibody für IF, IHC (p) - ABIN197046 : Kubota, Obata, Ota, Sasaki, Ito: Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 2 Referenzen für 197046

  6. Human Polyclonal EIF2S1 Primary Antibody für IF, IHC (p) - ABIN319275 : de Haro, Méndez, Santoyo: The eIF-2alpha kinases and the control of protein synthesis. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996 (PubMed)
    Zeige alle 2 Referenzen für 319275

  7. Cow (Bovine) Polyclonal EIF2S1 Primary Antibody für IHC, WB - ABIN2778883 : Marciniak, Garcia-Bonilla, Hu, Harding, Ron: Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK. in The Journal of cell biology 2006 (PubMed)

  8. Cow (Bovine) Polyclonal EIF2S1 Primary Antibody für WB - ABIN2778882 : Puri, Mirshahi, Cheung, Natarajan, Maher, Kellum, Sanyal: Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease. in Gastroenterology 2008 (PubMed)

  9. Human Monoclonal EIF2S1 Primary Antibody für IF, RNAi - ABIN560711 : Weinlich, Hüttelmaier, Schierhorn, Behrens, Ostareck-Lederer, Ostareck: IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR. in RNA (New York, N.Y.) 2009 (PubMed)

Weitere Antikörper gegen EIF2S1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Interaktionspartner

  1. Therapeutic modulation of eIF2alpha phosphorylation rescues TDP-43 (zeige TARDBP Antikörper) toxicity in amyotrophic lateral sclerosis disease models.

Mouse (Murine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Interaktionspartner

  1. ER stress-induced increase in ATF4 (zeige ATF4 Antikörper) and CHOP (zeige DDIT3 Antikörper) expression is initiated by an increase in Atf4 (zeige ATF4 Antikörper) and Chop (zeige DDIT3 Antikörper) mRNA, which is also dependent upon eIF2alpha (zeige EIF2A Antikörper) phosphorylation.

  2. Data indicate that 5xFAD-related pathologies do not necessarily require hyperphosphorylation of eIF2alpha (zeige EIF2A Antikörper) to emerge.

  3. Endoplasmic reticulum stress suppressed CReP (zeige PPP1R15B Antikörper) expression in an IRE1 alpha (zeige ERN1 Antikörper)-dependent manner, which increased eIF2alpha (zeige EIF2A Antikörper) phosphorylation and consequently attenuated protein synthesis.

  4. eIF2alphaP acts as a molecular switch that dictates either cell survival or death by activated Akt (zeige AKT1 Antikörper) in response to oxidative stress.

  5. aberrant phosphorylation of eukaryotic initiation factor (zeige EIF4G1 Antikörper)-2a (eIF2a (zeige EIF2A Antikörper)) may induce synaptic failure and neurodegeneration through persistent translational inhibition of global protein synthesis.

  6. Alteration of protein homeostasis and eIF2alpha (zeige EIF2A Antikörper) phosphorylation status by pathogenic huntingtin (zeige HTT Antikörper) appears to be an important cause of striatal cell death.

  7. Data indicate that prolonged endoplasmic reticulum stress inhibits protein synthesis independently of translation initiation factor eIF2alpha (zeige EIF2A Antikörper)-P.

  8. This study demonistrated that Genetic deletion of eIF2alpha (zeige EIF2A Antikörper) kinase PERK (zeige EIF2AK3 Antikörper) prevented enhanced phosphorylation of eIF2alpha (zeige EIF2A Antikörper) and deficits in protein synthesis, synaptic plasticity and spatial memory in animal disease model of Alzheimer's disease.

  9. eIF2alpha (zeige EIF2A Antikörper) phosphorylation in the context of the ER stress response plays a role in cell survival by counteracting the p53 (zeige TP53 Antikörper)-mediated mitochondrial apoptosis in response to statins.

  10. eIF2a (zeige EIF2A Antikörper) is hyperphosphorylated in the cortex of aged mice. Young human-ApoE4 targeted-replacement mice show increased p-eIF2a/eIF2a (zeige EIF2A Antikörper) levels in both cortex and hippocampus.

Pig (Porcine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Interaktionspartner

  1. In conclusion, the immediate-early (zeige JUN Antikörper) IE180 protein of pseudorabies virus has the previously uncharacterized ability to suppress phosphorylation levels of the eukaryotic translation initiation factor (zeige EIF2A Antikörper) eIF2alpha (zeige EIF2A Antikörper).

Human Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Interaktionspartner

  1. These data indicate that PERK (zeige EIF2AK3 Antikörper) regulates radioresistance in oropharyngeal carcinoma through NF-kB activation-mediated phosphorylation of eIF2alpha (zeige EIF2A Antikörper)

  2. The stem-loop of noncoding RNA 886 is structural feature not only critical for inhibiting PKR (zeige PKLR Antikörper) autophosphorylation, but also the phosphorylation of its cellular substrate, EIF-2alpha.

  3. overexpression of eIF5 (zeige EIF5 Antikörper) and 5MP induces translation of ATF4 (zeige ATF4 Antikörper).

  4. Through pathway analysis it was suggested the involvement of eIF2 and mTOR (zeige FRAP1 Antikörper) in host cells upon Chlamydia trachomatis infection.

  5. PERK (zeige EIF2AK3 Antikörper)-eIF2alpha (zeige EIF2A Antikörper)-ATF4 (zeige ATF4 Antikörper) signaling pathway mediated by endoplasmic reticulum stress involved in osteoblast differentiation of periodontal ligament cells under cyclic mechanical force.

  6. EnR (zeige LARGE Antikörper) stress assessed by expression of PERK (zeige EIF2AK3 Antikörper) and p-eIF2alpha (zeige EIF2A Antikörper) was significantly associated with tumor infiltrating lymphocytes (TILs) in HER2 (zeige ERBB2 Antikörper)-positive breast cancer.

  7. we unravels a new miRs-based mechanism that helps maintain intracellular proteostasis and promote cell survival during ER stress through upregulation of miR (zeige MLXIP Antikörper)-30b-5p and miR (zeige MLXIP Antikörper)-30c-5p which target eIF2alpha (zeige EIF2A Antikörper) and thereby inhibit the p-eIF2alpha (zeige EIF2A Antikörper)/ATF4 (zeige ATF4 Antikörper)/CHOP (zeige DDIT3 Antikörper) pro-apoptotic pathway, identifying miR (zeige MLXIP Antikörper)-30b-5p and miR (zeige MLXIP Antikörper)-30c-5p as potentially new targets for anti-cancer therapies.

  8. Our work suggests that OLA1 (zeige OLA1 Antikörper) is a novel translational GTPase (zeige RACGAP1 Antikörper) and plays a suppressive role in translation and cell survival, as well as cancer growth and progression.

  9. a delay in eIF2-bound GTP (zeige AK3 Antikörper) hydrolysis should occur. In this work, we reconstructed this situation and found that such a delay leads to the redistribution of initiation complexes in favor to downstream AUG codons.

  10. The reactive oxygen species-generating NADPH oxidase-4 (Nox4 (zeige NOX4 Antikörper)) is induced downstream of ATF4 (zeige ATF4 Antikörper), binds to a PP1 (zeige PPA1 Antikörper)-targeting subunit GADD34 (zeige PPP1R15A Antikörper) at the endoplasmic reticulum, and inhibits PP1 (zeige PPA1 Antikörper) activity to increase eIF2alpha (zeige EIF2A Antikörper) phosphorylation and ATF4 (zeige ATF4 Antikörper) levels.

Cow (Bovine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Interaktionspartner

  1. Caspase (zeige CASP3 Antikörper)(s)-dependent proteolysis of molecular chaperones and eIF2alpha (zeige EIF2A Antikörper) may be novel signaling pathways of apoptosis.

EIF2S1 Antigen-Profil

Beschreibung des Gens

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2\; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3\; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987

Alternative names and synonyms associated with EIF2S1

  • eukaryotic translation Initiation Factor 2alpha (eIF-2alpha) Antikörper
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (eif2s1) Antikörper
  • eukaryotic translation initiation factor 2 alpha subunit (LOC693063) Antikörper
  • eukaryotic translation initiation factor 2 alpha subunit (CNI00230) Antikörper
  • eukaryotic translation initiation factor 2 alpha subunit (THAPSDRAFT_105) Antikörper
  • Eukaryotic translation initiation factor 2 subunit 1 (if2a) Antikörper
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (LOC100339093) Antikörper
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (LOC100350462) Antikörper
  • eukaryotic translation initiation factor 2 subunit 1 (if2a) Antikörper
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1) Antikörper
  • eukaryotic translation initiation factor 2, subunit 1 alpha (Eif2s1) Antikörper
  • eukaryotic translation initiation factor 2, subunit 1 alpha (LOC100155472) Antikörper
  • eukaryotic translation initiation factor 2, subunit 1 alpha b (eif2s1b) Antikörper
  • 35kDa Antikörper
  • 0910001O23Rik Antikörper
  • 2410026C18Rik Antikörper
  • CG9946 Antikörper
  • deIF2alpha Antikörper
  • Dmel\\CG9946 Antikörper
  • EIF-2 Antikörper
  • eIF-2 a Antikörper
  • eIF-2 alpha Antikörper
  • EIF-2A Antikörper
  • EIF-2alpha Antikörper
  • EIF2 Antikörper
  • eIF2 alpha Antikörper
  • eIF2-alpha Antikörper
  • EIF2A Antikörper
  • eIF2alpha Antikörper
  • eif2s1 Antikörper
  • elF2alpha Antikörper
  • fb19d01 Antikörper
  • IF2A_DROME Antikörper
  • l(1)14Cf Antikörper
  • l(1)19-153 Antikörper
  • M(1)8e3-10 Antikörper
  • M(1)14C Antikörper
  • M(1)19-153 Antikörper
  • wu:fb19d01 Antikörper

Bezeichner auf Proteinebene für EIF2S1

CG9946-PA , eIF-2alpha-PA , eukaryotic initiation factor 2alpha , eukaryotic translation initiation factor 2 , eukaryotic translation initiation factor 2alpha , minute (1) 14C , EIF-2A , EIF-2alpha , eIF-2-alpha , eukaryotic translation initiation factor 2 subunit 1 , eukaryotic translation initiation factor 2 subunit alpha , eukaryotic translation initiation factor 2 alpha subunit , Eukaryotic translation initiation factor 2 subunit 1 , eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa , eIF-2A , eIF-2alpha , eukaryotic translation initiation factor 2A , eIF2 alpha subunit , eukaryotic translation initiation factor 2, subunit 1 (alpha )

GENE ID SPEZIES
32617 Drosophila melanogaster
448087 Xenopus (Silurana) tropicalis
693063 Bombyx mori
3259501 Cryptococcus neoformans var. neoformans JEC21
7449310 Thalassiosira pseudonana CCMP1335
100195154 Salmo salar
100339093 Oryctolagus cuniculus
100350462 Oryctolagus cuniculus
100528138 Ictalurus punctatus
100587728 Nomascus leucogenys
13665 Mus musculus
54318 Rattus norvegicus
100155472 Sus scrofa
321564 Danio rerio
1965 Homo sapiens
380444 Xenopus laevis
423279 Gallus gallus
480361 Canis lupus familiaris
327694 Bos taurus
100174029 Pongo abelii
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