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RBP4 Proteine (RBP4)

Bezeichnung:
Retinol Binding Protein 4, Plasma Proteine (RBP4)
Auf www.antikoerper-online.de finden Sie aktuell 71 Retinol Binding Protein 4, Plasma (RBP4) Proteine von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RBP4 Antikörper (483) und RBP4 Kits (113) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 695 RBP4 Produkte verfügbar.
Synonyme:
2310002G05Rik, 2610028L19Rik, HSRBP4, MGC54038, PRBP, RBP, Rbp-4, RBP4, RBPA, RDCCAS, RNBP, srbp
alle Proteine anzeigen Gen GeneID UniProt
RBP4 69241 Q9D7M8
RBP4 5973 P51606
RBP4 25703 P04916

Weitere Synonyme anzeigen

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Am meisten referenzierte RBP4 Proteine

  1. Human RBP4 Protein expressed in Human Cells - ABIN2002658 : Colantuoni, Romano, Bensi, Santoro, Costanzo, Raugei, Cortese: Cloning and sequencing of a full length cDNA coding for human retinol-binding protein. in Nucleic acids research 1984 (PubMed)
    Zeige alle 8 Referenzen für ABIN2002658

  2. Mouse (Murine) RBP4 Protein expressed in Human Cells - ABIN2007447 : Quadro, Blaner, Hamberger, Van Gelder, Vogel, Piantedosi, Gouras, Colantuoni, Gottesman: Muscle expression of human retinol-binding protein (RBP). Suppression of the visual defect of RBP knockout mice. in The Journal of biological chemistry 2002 (PubMed)
    Zeige alle 6 Referenzen für ABIN2007447

  3. Cynomolgus RBP4 Protein expressed in Human Cells - ABIN2010004 : Zanotti, Berni: Plasma retinol-binding protein: structure and interactions with retinol, retinoids, and transthyretin. in Vitamins and hormones 2004 (PubMed)
    Zeige alle 5 Referenzen für ABIN2010004

  4. Human RBP4 Protein expressed in CHO Cells - ABIN2666743 : Frey, Nagl, Henze, Raila, Schlosser, Berg, Tepel, Zidek, Weickert, Pfeiffer, Schweigert: Isoforms of retinol binding protein 4 (RBP4) are increased in chronic diseases of the kidney but not of the liver. in Lipids in health and disease 2008 (PubMed)
    Zeige alle 5 Referenzen für ABIN2666743

  5. Rat (Rattus) RBP4 Protein expressed in Human Cells - ABIN2009021 : Cho, Youn, Lee, Lee, Min, Kwak, Lee, Park: Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes. in Diabetes Care 2006 (PubMed)
    Zeige alle 5 Referenzen für ABIN2009021

  6. Dog (Canine) RBP4 Protein expressed in Human Cells - ABIN2008839 : Balagopal, Graham, Kahn, Altomare, Funanage, George: Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation. in The Journal of clinical endocrinology and metabolism 2007 (PubMed)
    Zeige alle 5 Referenzen für ABIN2008839

  7. Human RBP4 Protein expressed in Escherichia coli (E. coli) - ABIN1047604 : DOnofrio, Colantuoni, Cortese: Structure and cell-specific expression of a cloned human retinol binding protein gene: the 5'-flanking region contains hepatoma specific transcriptional signals. in The EMBO journal 1986 (PubMed)
    Zeige alle 3 Referenzen für ABIN1047604

  8. Rat (Rattus) RBP4 Protein expressed in Human - ABIN1344327 : Casillas-Ramírez, Alfany-Fernández, Massip-Salcedo, Juan, Planas, Serafín, Pallàs, Rimola, Rodés, Peralta: Retinol-binding protein 4 and peroxisome proliferator-activated receptor-? in steatotic liver transplantation. in The Journal of pharmacology and experimental therapeutics 2011 (PubMed)

Weitere Proteine zu RBP4 Interaktionspartnern

Mouse (Murine) Retinol Binding Protein 4, Plasma (RBP4) Interaktionspartner

  1. Rbp4-deficient mice accumulated retinol in the liver but it was undetectable in the serum, indicating an inverse relation between serum and liver retinol levels. RBP4 is critical for the mobilization of retinol from hepatic storage pools, and such mobilization is necessary for ocular development and visual function.

  2. Hepatocytes Are the Principal Source of Circulating RBP4 in Mice

  3. RBP4 may be a critical modulator promoting the vicious cycle of insulin (zeige INS Proteine) resistance and heart failure by activating TLR4 (zeige TLR4 Proteine)/MyD88 (zeige MYD88 Proteine)-mediated inflammatory pathways. Potentially, lowering RBP4 might break the vicious cycle and improve both insulin (zeige INS Proteine) resistance and cardiac hypertrophy.

  4. Data (including data from studies in knockout mice) suggest that Rbp4 (plasma retinol-binding protein 4) is critical for antigen presentation and activation of CD4 (zeige CD4 Proteine)-positive T-lymphocyte in development of insulin (zeige INS Proteine) resistance in mice obese due to high-fat diet.

  5. A novel mechanism for circadian regulation of RBP4, but also a critical role of RBP4, acting as a hepatokine in the regulation of glucose metabolism by the circadian clock.

  6. Elevated serum RBP4 raises BP.

  7. These data show that decreasing circulating TTR (zeige TTR Proteine) levels or altering TTR (zeige TTR Proteine)-RBP4 binding could be a potential therapeutic approach for the treatment of type 2 diabetes.

  8. findings suggest that RBP4 impaired in vivo adipogenesis, partly through the repression of the insulin (zeige INS Proteine) pathway

  9. The data implicate the involvement of chondrocytic Rbp4 in bone growth, particularly in the formation of the secondary ossification center of the limb.

  10. Rbp4 and its membrane receptor STRA6 control adipogenesis by regulating cellular retinoid homeostasis and RARalpha (zeige RARA Proteine) activity.

Human Retinol Binding Protein 4, Plasma (RBP4) Interaktionspartner

  1. Data show that the tissue-specific expression pattern of human transgenic retinol binding protein 4 (hRBP4orf) was roughly the same as that of mouse Rbp4 (zeige POLR2D Proteine).

  2. Elevated levels of RBP4 (zeige POLR2D Proteine) are associated with higher cardiovascular mortality among men with type 2 diabetes.

  3. RBP4 (zeige POLR2D Proteine) and retinol levels were increased approximately twofold in patients with chronic kidney disease.

  4. RBP4 (zeige POLR2D Proteine) level was associated with increased arterial stiffness in young subjects with family history of type 2 diabetes.

  5. Retinol-binding protein 4 is able to function as biomarker to distinguish severe pre-eclampsia from normal pregnancy. More importantly, these results may shed light on the role of Retinol-binding protein 4 in the pathogenesis in pre-eclampsia.

  6. The production of the two adipokines, chemerin and RBP-4, is strongly associated with obesity in patients with NAFLD.

  7. High level of RBP4 (zeige POLR2D Proteine) is associated with obesity.

  8. The positive association between circulating RBP4 (zeige POLR2D Proteine) and ApoB (zeige APOB Proteine)-containing lipoproteins in a steady metabolic state, as well as during a hypocaloric diet, appears to be attenuated in patients with very high serum triglycerides.

  9. Urinary KNG1 and RBP4 clearly respond to AKI. Additionally, RBP4 could predict recovery by monitoring this protein levels over time after AKI, as RBP4 reflects patient's normalization earlier than sCr values do.

  10. Serum RBP4 (zeige POLR2D Proteine) is negatively related to estrogen in Chinese women with obesity.

Cow (Bovine) Retinol Binding Protein 4, Plasma (RBP4) Interaktionspartner

  1. progesterone modulates uterine RBP4 mRNA and protein abundance in a time- and concentration-dependent manner.

  2. Two novel single nucleotide polymorphisms (SNPs) and 4-bp deletion mutation of RBP4 gene in Chinese cattle

  3. results suggest that retinol-binding protein 4 is transferred from maternal stores to calves through colostrum

  4. Serum albumin (zeige ALB Proteine) and serum retinol-binding protein(sRBP) are not components of bovine interphotoreceptor matrix(IPM). Serum albumin (zeige ALB Proteine) and sRBP can not participate in binding and transport of visual cycle retinoids in IPM of bovine retina.

Pig (Porcine) Retinol Binding Protein 4, Plasma (RBP4) Interaktionspartner

  1. There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found.

  2. RBP4 has a role in adipogenesis of porcine preadipocytes through the insulin (zeige INS Proteine) signaling pathways

  3. Data show that there were two genotypes for RBP4 gene in Tibet pig, which did not have significant effect on the reproductive traits.

  4. The aim of this work was to study the effects on litter size of variants of the porcine genes RBP4, ESR1 and IGF2, currently used in genetic tests for different purposes.

  5. Response to selection for increased litter size could not be attributed to effects at the estrogen receptor (zeige ESR1 Proteine), retinol-binding protein or follistatin (zeige FST Proteine) loci.

  6. study found significant association of two diallelic polymorphisms in the porcine genes for leukaemia inhibitory factor (LIF (zeige LIF Proteine)) and retinol-binding protein 4 (RBP4) with number of piglets born alive (NBA) in two German pig lines

  7. The results showed that the polymorphic sites of both PRLR (zeige PRLR Proteine) and RBP4 genes are closely related to litter size traits.

RBP4 Protein Überblick

Protein Überblick

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Alternative names and synonyms associated with RBP4

  • retinol binding protein 4, plasma (rbp4)
  • polymerase (RNA) II (DNA directed) polypeptide D (Polr2d)
  • renin binding protein (RENBP)
  • retinol binding protein 4, plasma (RBP4)
  • retinol binding protein 4, plasma (Rbp4)
  • 2310002G05Rik Protein
  • 2610028L19Rik Protein
  • HSRBP4 Protein
  • MGC54038 Protein
  • PRBP Protein
  • RBP Protein
  • Rbp-4 Protein
  • RBP4 Protein
  • RBPA Protein
  • RDCCAS Protein
  • RNBP Protein
  • srbp Protein

Bezeichner auf Proteinebene für RBP4

retinol-binding protein 4, plasma , DNA-directed RNA polymerase II subunit D , DNA-directed RNA polymerase II subunit RPB4 , RNA polymerase II subunit B4 , AGE , GlcNAc 2-epimerase , N-acetyl-D-glucosamine 2-epimerase , N-acylglucosamine 2-epimerase , PRBP , RBP , plasma retinol-binding protein , retinol-binding protein 4 , retinol-binding protein 4, interstitial , retinol binding protein 4, cellular , Plasma retinol-binding protein , serum retinol binding protein

GENE ID SPEZIES
380159 Xenopus laevis
548465 Xenopus (Silurana) tropicalis
69241 Mus musculus
5973 Homo sapiens
5950 Homo sapiens
19662 Mus musculus
25703 Rattus norvegicus
100009161 Oryctolagus cuniculus
477775 Canis lupus familiaris
396166 Gallus gallus
281444 Bos taurus
100725967 Cavia porcellus
397124 Sus scrofa
100049790 Equus caballus
101105458 Ovis aries
397705 Xenopus laevis
450617 Pan troglodytes
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