anti-Ratte (Rattus) TAP2 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended TAP2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) Antikörper
  • ABC18
  • ABCB3
  • APT2
  • D6S217E
  • PSF-2
  • PSF2
  • RING11
  • AI462429
  • Abcb3
  • Ham-2
  • Ham2
  • MTP2
  • Tap-2
  • Y1
  • jas
  • Cim
  • transporter 2, ATP binding cassette subfamily B member
  • transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
  • TAP2
  • Tap2
Reaktivität
Human, Maus, Ratte (Rattus)
88
42
41
Wirt
Kaninchen
84
3
2
Klonalität
Polyklonal
Konjugat
Dieser TAP2 Antikörper ist unkonjugiert
5
5
5
3
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
39
36
26
25
17
14
7
5
4
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN680123
$ 306.90
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN680132 IHC (p) WB HRP Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN680125 IHC (p) WB Biotin Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN2879811 IF IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN912396 IHC (p) WB HRP Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN912401 IHC (p) WB Biotin Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN872646 IF (p) IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(88), (42), (41)
Wirt Kaninchen
(84), (3), (2)
Klonalität
Polyklonal
Konjugat Dieser TAP2 Antikörper ist unkonjugiert
(5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(39), (36), (26), (25), (17), (14), (7), (5), (4), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TAP2 Antikörper

Target Details TAP2 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human TAP2
Isotyp IgG

Target Details TAP2

Produktdetails anti-TAP2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Tap2 (TAP2 Antibody Abstract)
Hintergrund

TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.

Subcellular location: Cytoplasm

Synonyms: Uncharacterized protein C9orf172, C9orf172

Gen-ID 389813
UniProt C9J069
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process

Anwendungsinformationen

Produktdetails anti-TAP2 Antikörper Target Details TAP2 Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TAP2 Antikörper Target Details TAP2 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-TAP2 Antikörper Target Details TAP2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibody (ABIN680123) Formalin-fixed and paraffin embedded human endometrial carcinoma labeled with Anti TA...
SDS-PAGE (SDS) image for anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibody (ABIN680123) Lane 1: mouse intestine lysates Lane 2: mouse lung lysates probed with Anti TAP2/ABCB...
Flow Cytometry (FACS) image for anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibody (ABIN680123) Fixed and permeabilized EL-4 cells were labeled with Rabbit Anti- TAP2/ABCB3 Polyclon...