anti-Maus P2RX7 Antikörper für Flow Cytometry

Recommended P2RX7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper
  • p2xr7
  • P2RX7
  • P2X7
  • AI467586
  • P2X(7)
  • P2X7R
  • p2x7
  • purinergic receptor P2X 7
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • P2X purinoceptor 7
  • P2RX7
  • p2rx7
  • LOC100458463
  • P2rx7
Reaktivität
Maus
94
77
39
5
4
4
4
3
3
2
2
Wirt
Ratte
78
24
19
2
Klonalität
Monoklonal
Konjugat
Dieser P2RX7 Antikörper ist unkonjugiert
8
4
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
77
50
41
25
24
20
18
13
2
1
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2665313
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2476005 FACS FITC Rat IgG2b Anmelden zum Anzeigen Hano43 4
1 ABIN2476002 FACS IF Rat IgG2b Anmelden zum Anzeigen Hano43 4
1 ABIN1820067 FACS IF FITC Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN1820068 FACS IF Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN1832796 FACS Rat IgG2b Anmelden zum Anzeigen HANO43
1 ABIN4342636 FACS APC Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342626 FACS ICC IF Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN2476003 FACS Alexa Fluor 488 Rat IgG2b Anmelden zum Anzeigen Hano43 4
1 ABIN2476004 FACS Alexa Fluor 647 Rat IgG2b Anmelden zum Anzeigen Hano43 4
1 ABIN4342634 FACS PE Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342633 FACS ICC IF DyLight 405 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342632 FACS ICC IF DyLight 350 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342635 FACS ICC IF PerCP Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342637 FACS ICC IF DyLight 755 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342638 FACS ICC IF DyLight 680 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342642 FACS ICC IF Alexa Fluor 488 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342644 FACS ICC IF Alexa Fluor 700 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342641 FACS ICC IF Alexa Fluor 405 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342643 FACS ICC IF Alexa Fluor 647 Rat IgG2b Anmelden zum Anzeigen Hano43
1 ABIN4342639 FACS ICC IF DyLight 488 Rat IgG2b Anmelden zum Anzeigen Hano43

General

Antigen Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper
Reaktivität Maus
(94), (77), (39), (5), (4), (4), (4), (3), (3), (2), (2)
Wirt Ratte
(78), (24), (19), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser P2RX7 Antikörper ist unkonjugiert
(8), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS)
(77), (50), (41), (25), (24), (20), (18), (13), (2), (1), (1), (1)
Pubmed 8 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-P2RX7 Antikörper

Target Details P2RX7 Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2665313) Bilder
Reinigung The antibody was purified by affinity chromatography.
Klon 1F11
Isotyp IgG2b kappa

Target Details P2RX7

Produktdetails anti-P2RX7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2665313) Bilder zurück nach oben
Antigen
Andere Bezeichnung P2X7R (P2RX7 Antibody Abstract)
Hintergrund P2X7R, also known as P2X7 receptor, belongs to the family of ligand-gated ion channel receptors. It is expressed on T cells, B cells, macrophages, and microglia. The receptor opens in the presence of extracellular ATP or NAD, leading to intracellular calcium mobilization. P2X7R activation requires higher concentrations of ATP compared to other P2X receptors. Longer stimulation results in larger pores, allowing passage of larger molecules. Activation of these molecules also leads to mitochondrial and cytoskeletal changes as well as IL-1β maturation and release. Ligation of P2X7 receptor can lead to membrane blebbing and cell death.
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis

Anwendungsinformationen

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2665313) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Referenzen für anti-P2RX7 Antikörper (ABIN2665313) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-P2RX7 Antikörper (ABIN2665313)

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Alves, de Melo Reis, de Souza, de Freitas, Teixeira, Neto Moreira Ferreira, Xavier: "The P2X7 receptor: shifting from a low- to a high-conductance channel - an enigmatic phenomenon?" in: Biochimica et biophysica acta, Vol. 1838, Issue 10, pp. 2578-87, 2014

Bartlett, Stokes, Sluyter: "The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease." in: Pharmacological reviews, Vol. 66, Issue 3, pp. 638-75, 2014

Kurashima, Amiya, Nochi, Fujisawa, Haraguchi, Iba, Tsutsui, Sato, Nakajima, Iijima, Kubo, Kunisawa, Kiyono: "Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors." in: Nature communications, Vol. 3, pp. 1034, 2012

Pelegrín: "Many ways to dilate the P2X7 receptor pore." in: British journal of pharmacology, Vol. 163, Issue 5, pp. 908-11, 2011

Kawamura, Aswad, Minagawa, Govindarajan, Dennert: "P2X7 receptors regulate NKT cells in autoimmune hepatitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 4, pp. 2152-60, 2006

Gargett, Cornish, Wiley: "ATP, a partial agonist for the P2Z receptor of human lymphocytes." in: British journal of pharmacology, Vol. 122, Issue 5, pp. 911-7, 1998

Surprenant, Rassendren, Kawashima, North, Buell: "The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)." in: Science (New York, N.Y.), Vol. 272, Issue 5262, pp. 735-8, 1996

Chused, Apasov, Sitkovsky: "Murine T lymphocytes modulate activity of an ATP-activated P2Z-type purinoceptor during differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 4, pp. 1371-80, 1996

Bilder

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2665313) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) antibody (ABIN2665313) anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) antibody
Flow Cytometry (FACS) image for anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) antibody (ABIN2665313) anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) antibody (Image 2)