anti-Meerschweinchen P2RX7 Antikörper für Immunohistochemistry

Recommended P2RX7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper
  • p2xr7
  • P2RX7
  • P2X7
  • AI467586
  • P2X(7)
  • P2X7R
  • p2x7
  • purinergic receptor P2X 7
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • P2X purinoceptor 7
  • P2RX7
  • p2rx7
  • LOC100458463
  • P2rx7
Epitop
N-Term
20
18
14
4
4
3
3
3
2
2
2
2
2
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
93
77
38
4
4
3
3
2
2
2
2
Wirt
Kaninchen
77
25
19
2
Klonalität
Polyklonal
Konjugat
Dieser P2RX7 Antikörper ist unkonjugiert
8
4
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
76
49
41
26
24
20
18
13
2
1
1
1
Optionen
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Bilder

Produktnummer ABIN2776335
$ 229.00
Zzgl. Versandkosten $45.00

General

Antigen Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antikörper
Epitop N-Term
(20), (18), (14), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(93), (77), (38), (4), (4), (3), (3), (2), (2), (2), (2)
Wirt Kaninchen
(77), (25), (19), (2)
Klonalität
Polyklonal
Konjugat Dieser P2RX7 Antikörper ist unkonjugiert
(8), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(76), (49), (41), (26), (24), (20), (18), (13), (2), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-P2RX7 Antikörper

Target Details P2RX7 Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776335) Bilder
Sequenz IQSMNYGTIK WFFHVIIFSY VCFALVSDKL YQRKEPVISS VHTKVKGIAE
Homologie Cow: 93%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against P2RX7. It was validated on Western Blot and immunohistochemistry.
Reinigung Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human P2RX7

Target Details P2RX7

Produktdetails anti-P2RX7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776335) Bilder zurück nach oben
Antigen
Andere Bezeichnung P2RX7 (P2RX7 Antibody Abstract)
Hintergrund The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Alias Symbols: P2X7
Protein Interaction Partner: KRTAP10-8, KRT31, TM9SF1, CASK, EFNB3, EMP3, PANX1, SVIL, ACTB,
Protein Size: 595
Molekulargewicht 69 kDa
Gen-ID 5027
UniProt Q99572
Forschungsgebiet Neurology
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis

Anwendungsinformationen

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776335) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 595 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Referenzen für anti-P2RX7 Antikörper (ABIN2776335) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-P2RX7 Antikörper (ABIN2776335)

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Schneider, Glaser, Lameu, Abdelbaset-Ismail, Sellers, Moniuszko, Ulrich, Ratajczak: "Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells." in: Molecular cancer, Vol. 14, pp. 201, 2015

Allgemeine Veröffentlichungen

Buell, Talabot, Gos, Lorenz, Lai, Morris, Antonarakis: "Gene structure and chromosomal localization of the human P2X7 receptor." in: Receptors & channels, Vol. 5, Issue 6, pp. 347-54, 1999

Bilder

Produktdetails anti-P2RX7 Antikörper Target Details P2RX7 Anwendungsinformationen Handhabung Referenzen für anti-P2RX7 Antikörper (ABIN2776335) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibody (ABIN2776335) WB Suggested Anti-P2RX7 Antibody Titration: 1.25ug/ml
ELISA Titer: 1...
Immunohistochemistry (IHC) image for anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibody (ABIN2776335) anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibody (Image 2)