anti-SAG (SAG) Antikörper

anti-S-Antigen, Retina and Pineal Gland (Arrestin) Antikörper (SAG)
Auf finden Sie aktuell 76 S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SAG Kits (25) und SAG Proteine (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 114 SAG Produkte verfügbar.
A930001K18Rik, ARR, Arr1, arrestin, Irbp, MGC75721, MGC84416, RP47, S-AG, sag, sag1, SAGMR, SANTI, zgc:114197

Meistgesuchte Reaktivitäten zu anti-SAG (SAG) Antikörper

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anti-Mouse (Murine) SAG Antikörper:

anti-Human SAG Antikörper:

anti-Rat (Rattus) SAG Antikörper:

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Am meisten referenzierte anti-SAG Antikörper

  1. Human Monoclonal SAG Primary Antibody für ICC, IF - ABIN1580413 : Dorey, Faure: [Isolation and characterization of a retinal antigen inducing experimental autoimmune uveo-retinitis]. in Annales d'immunologie 1977 (PubMed)
    Zeige alle 4 Referenzen für 1580413

  2. Cow (Bovine) Monoclonal SAG Primary Antibody für ICC, IHC (fro) - ABIN250780 : Banga, LeRoy, Suleyman, Kasp, Brown, Dumonde: Analysis of antigenic determinants of retinal S-antigen with monoclonal antibodies. in Investigative ophthalmology & visual science 1988 (PubMed)
    Zeige alle 3 Referenzen für 250780

  3. Rat (Rattus) Monoclonal SAG Primary Antibody für ICC, IHC (fro) - ABIN108637 : Banga, Suleyman, Kasp, Brown, LeRoy, Sanders, Dumonde: Immunoaffinity purification of S-antigen using monoclonal antibodies to different antigenic sites. in Investigative ophthalmology & visual science 1987 (PubMed)
    Zeige alle 2 Referenzen für 108637

Weitere Antikörper gegen SAG Interaktionspartner

Mouse (Murine) S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) Interaktionspartner

  1. The G-protein coupled receptor, DRD4, requires ARR1 and ARR4 for desensitization and internalization.

  2. ARR4 modulates essential functions in high acuity vision and downstream cellular signaling pathways that are not fulfilled or substituted by the coexpression of ARR1, despite its high expression levels in all mouse cones.

  3. crystal structure of a constitutively active form of human rhodopsin (zeige RHO Antikörper) bound to a pre-activated form of the mouse visual arrestin, determined by serial femtosecond X-ray laser crystallography

  4. Sag (zeige RNF7 Antikörper) is essential for embryonic vasculogenesis and tumor angiogenesis.

  5. SAG (zeige RNF7 Antikörper) knockdown caused the accumulation of proapoptotic Bax (zeige BAX Antikörper) and SARM (zeige SARM1 Antikörper), imbalance of Bcl-2 (zeige BCL2 Antikörper)/Bax (zeige BAX Antikörper) in the mitochondria, induction of cytosolic cytochrome c (zeige CYCS Antikörper) and activation of caspases, all of which led to disequilibrium between life and death of macrophages.

  6. tetrameric visual arrestin 1 is a biomarker for retinal function in diabetic mice, assessed by MRI (zeige C7ORF49 Antikörper)

  7. The data suggest that monomeric arrestin-1 is cytotoxic and WT arrestin-1 protects rods by forming mixed oligomers with the mutant and/or competing with it for the binding to non-receptor partners.

  8. Findings suggest a role for Bardet-Biedl syndrome 5 (BBS5) in regulating light-dependent translocation of arrestin1 (Arr1).

  9. Visual arrestin interaction with clathrin adaptor AP-2 (zeige TFAP2A Antikörper) regulates photoreceptor survival in the vertebrate retina.

  10. the 139-loop stabilizes basal conformation of arrestin-1 and acts as a brake, preventing its binding to non-preferred forms of rhodopsin (zeige RHO Antikörper).

Human S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) Interaktionspartner

  1. This is the first dominant-acting mutation identified in SAG (zeige DMBT1 Antikörper), a founder mutation possibly originating in Mexico several centuries ago. The phenotype is clearly adRP (zeige PLIN2 Antikörper) and is distinct from the previously reported phenotypes of recessive null mutations, that is, Oguchi disease and recessive RP.

  2. Macular dysfunction can occur in Oguchi disease with the 1147delA mutation in the SAG (zeige DMBT1 Antikörper) gene.

  3. NEDD4-1 (zeige NEDD4 Antikörper) overexpression sensitizes cancer cells to etoposide-induced apoptosis by reducing SAG (zeige DMBT1 Antikörper) levels through targeted degradation. SAG (zeige DMBT1 Antikörper) is added to a growing list of NEDD4-1 (zeige NEDD4 Antikörper) substrates and mediates its biological function.

  4. Sag (zeige DMBT1 Antikörper) is a Kras-cooperating oncogene (zeige RAB1A Antikörper) that promotes lung tumorigenesis

  5. Based on their observed affinity for arrestin-1, P-opsin (zeige RHO Antikörper) and inactive P-Rh very likely affect the physiological monomer-dimer-tetramer equilibrium of arrestin-1, and should therefore be taken into account when modeling photoreceptor function.

  6. Compound heterozygosity of a nonsense R193X mutation and a heterozygous deletion of 3,224 bp encompassing exon 2 in the SAG (zeige DMBT1 Antikörper) gene is the cause of Oguchi's disease in a Chinese family.

  7. Identification of autoantibodies specific for two retinal antigens (CRALBP (zeige RLBP1 Antikörper) and S-Ag) supports the concept of an autoimmunological origin of the disease.

  8. the arrestin 1147delA, which has been known as a frequent cause of Oguchi disease, also may be related to the pathogenesis of autosomal recessive RP.

  9. We describe a case of Oguchi disease with unusual findings caused by a putative heterozygous mutation in the SAG (zeige DMBT1 Antikörper) gene.

  10. maintenance of low levels of the active monomer is the biological role of arrestin-1 self-association

Cow (Bovine) S-Antigen, Retina and Pineal Gland (Arrestin) (SAG) Interaktionspartner

  1. Conformational changes are involved in the arrestin-rhodopsin (zeige RHO Antikörper) binding interface through multiple docking modes.

  2. K2A mutations in arrestin-1, -2, and -3 significantly reduced their binding to active phosphorhodopsin.

  3. maintenance of low levels of the active monomer is the biological role of arrestin-1 self-association

  4. We hypothesize that, although arrestin requires at least a single Rho*P to bind the membrane, a single arrestin can actually interact with a pair of receptors

  5. variant form of arrestin-1 binds rod outer segment membranes

  6. Models suggest that the phosphorylated carboxy-terminal region of rhodopsin (zeige RHO Antikörper), Rh(330-348), undergoes significant conformational changes and becomes structured upon binding to arrestin.

  7. arrestin and p44 bind differently to different phosphorylated rhodopsin species and that this may be due to a structural difference between p44's and arrestin's basal states.

SAG Antigen-Profil

Beschreibung des Gens

may act as a GTP/GDP-binding protein\; may play a role in signal transduction in the retina

Alternative names and synonyms associated with SAG

  • S-antigen; retina and pineal gland (arrestin) (sag) Antikörper
  • S-antigen; retina and pineal gland (arrestin) b (sagb) Antikörper
  • S-antigen (PF10_0343) Antikörper
  • S-antigen; retina and pineal gland (arrestin) (SAG) Antikörper
  • arrestin (sag) Antikörper
  • S-antigen, retina and pineal gland (arrestin) (Sag) Antikörper
  • S-antigen; retina and pineal gland (arrestin) (Sag) Antikörper
  • A930001K18Rik Antikörper
  • ARR Antikörper
  • Arr1 Antikörper
  • arrestin Antikörper
  • Irbp Antikörper
  • MGC75721 Antikörper
  • MGC84416 Antikörper
  • RP47 Antikörper
  • S-AG Antikörper
  • sag Antikörper
  • sag1 Antikörper
  • SAGMR Antikörper
  • SANTI Antikörper
  • zgc:114197 Antikörper

Bezeichner auf Proteinebene für SAG

S-antigen; retina and pineal gland (arrestin) , -antigen; retina and pineal gland (arrestin) , Arrestin Sb , S-antigen , s-arrestin-like , S-AG , S-arrestin , retinal S-antigen , rod photoreceptor arrestin , 48 kDa protein , arrestin 1 , rod arrestin , visual arrestin 1 , retinal S-antigen (48 KDa protein) , arrestin1 , arrestin, S-antigen

394670 Xenopus (Silurana) tropicalis
447588 Xenopus laevis
619268 Danio rerio
810500 Plasmodium falciparum 3D7
100445407 Pongo abelii
100598651 Nomascus leucogenys
398109 Xenopus laevis
20215 Mus musculus
6295 Homo sapiens
397151 Sus scrofa
280922 Bos taurus
25539 Rattus norvegicus
403906 Canis lupus familiaris
768877 Gallus gallus
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